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Biological Activities of Triterpene Saponins Mediated by Stimulating on Nervous System in Digestive Tract

Biological Activities of Triterpene Saponins Mediated by Stimulating on Nervous System in Digestive Tract
三萜皂苷通过刺激消化道神经系统介导的生物活性
批准号:
12672075
负责人:
YOSHIKAWA Masayuki
金额:
$2.43万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2000
资助国家:
日本
项目状态:
已结题
起止时间:
2000 至 2001

项目摘要

项目成果

YOSHIKAWA Masayuki的其他基金

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中文摘要
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英文摘要
Oleanolic acid (ex. momordine Ic) and acylated polyhydroxyolean-12-ene 3-monodesmosides (ex. escins) were found to have neither insulin-like nor insulin-releasing activity, but they inhibited gastric emptying and glucose-uptake in the small intestine. Investigation of the mode of action revealed that the inhibition of gastric emptying was mediated by capsaicin-sensitive sensory nerves and the stimulating the release and/or production of dopamine to act through dopamine, receptors, which in turn causes of prostaglandins.
期刊论文(64)
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会议论文
Masayuki Yoshikawa: "Antidiabetogenic Activity of Oleanolic Acid Glycosides from Medicinal Foodstuffs"Bio Factors. 13. 231-237 (2000)
Masayuki Yoshikawa:“药用食品中齐墩果酸苷的抗糖尿病活性”生物因素。
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Masayuki Yoshikawa: "Bioactive Saponins and Glycosides. XVI. Nortriterpene Oligoglycosides with Gastroprotective Activity from the Fresh Leaves of Euptelea polyandra SIEB.et Zucc.(I):Structures of Eupteleasaponins I, II, III, IV, V, and V Acetate"Chem.Pha
Masayuki Yoshikawa:“生物活性皂苷和糖苷。XVI.来自 Euptelea Polyandra SIEB.et Zucc 新鲜叶的具有胃保护活性的去甲三萜寡糖苷。(I):Eupteleasaponins I、II、III、IV、V 和 V 乙酸酯的结构”化学
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Toshiyuki Murakami: "Bioactive Saponins and Glycosides. XVII. Inhibitory Effect on Gastric Emptying and Accelerating Effect on Gastrointestinal Transit of Tea Saponins : Structures of Assamsaponins F, G, H, I, and J from the Seeds and Leaves of the Tea Pl
Toshiyuki Murakami:“生物活性皂苷和糖苷。XVII.茶皂苷对胃排空的抑制作用和对胃肠道转运的加速作用:来自茶树种子和叶子的阿参皂苷 F、G、H、I 和 J 的结构
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通讯作者:
Masayuki Yoshikawa el al.: "Bioactive Saponins and Glycosides. XVI. Nortriterpene Oligoglycosides with Gastroprotective Activity from the Fresh Leaves of Euplelea polyandra SIEB. et ZUCC. (1): Structures of Eupteleasaponins I, II, III. IV, V, and V Acetat
Masayuki Yoshikawa 等人:“生物活性皂苷和糖苷。XVI。来自 Euplelea Polyandra 新鲜叶的具有胃保护活性的去甲三萜寡糖苷 SIEB。等 ZUCC。(1):Eupteleasaponins I、II、III 的结构。IV、V 和 V
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