Biological Activities of Triterpene Saponins Mediated by Stimulating on Nervous System in Digestive Tract
Biological Activities of Triterpene Saponins Mediated by Stimulating on Nervous System in Digestive Tract
批准号:
12672075
负责人:
YOSHIKAWA Masayuki
金额:
$2.43万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2000
资助国家:
日本
项目状态:
已结题
起止时间:
2000 至 2001
中文摘要
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英文摘要
Oleanolic acid (ex. momordine Ic) and acylated polyhydroxyolean-12-ene 3-monodesmosides (ex. escins) were found to have neither insulin-like nor insulin-releasing activity, but they inhibited gastric emptying and glucose-uptake in the small intestine. Investigation of the mode of action revealed that the inhibition of gastric emptying was mediated by capsaicin-sensitive sensory nerves and the stimulating the release and/or production of dopamine to act through dopamine, receptors, which in turn causes of prostaglandins.
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Masayuki Yoshikawa: "Antidiabetogenic Activity of Oleanolic Acid Glycosides from Medicinal Foodstuffs"Bio Factors. 13. 231-237 (2000)
Masayuki Yoshikawa:“药用食品中齐墩果酸苷的抗糖尿病活性”生物因素。
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Masayuki Yoshikawa: "Bioactive Saponins and Glycosides. XVI. Nortriterpene Oligoglycosides with Gastroprotective Activity from the Fresh Leaves of Euptelea polyandra SIEB.et Zucc.(I):Structures of Eupteleasaponins I, II, III, IV, V, and V Acetate"Chem.Pha
Masayuki Yoshikawa:“生物活性皂苷和糖苷。XVI.来自 Euptelea Polyandra SIEB.et Zucc 新鲜叶的具有胃保护活性的去甲三萜寡糖苷。(I):Eupteleasaponins I、II、III、IV、V 和 V 乙酸酯的结构”化学
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Toshiyuki Murakami: "Bioactive Saponins and Glycosides. XVII. Inhibitory Effect on Gastric Emptying and Accelerating Effect on Gastrointestinal Transit of Tea Saponins : Structures of Assamsaponins F, G, H, I, and J from the Seeds and Leaves of the Tea Pl
Toshiyuki Murakami:“生物活性皂苷和糖苷。XVII.茶皂苷对胃排空的抑制作用和对胃肠道转运的加速作用:来自茶树种子和叶子的阿参皂苷 F、G、H、I 和 J 的结构
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Masayuki Yoshikawa el al.: "Bioactive Saponins and Glycosides. XVI. Nortriterpene Oligoglycosides with Gastroprotective Activity from the Fresh Leaves of Euplelea polyandra SIEB. et ZUCC. (1): Structures of Eupteleasaponins I, II, III. IV, V, and V Acetat
Masayuki Yoshikawa 等人:“生物活性皂苷和糖苷。XVI。来自 Euplelea Polyandra 新鲜叶的具有胃保护活性的去甲三萜寡糖苷 SIEB。等 ZUCC。(1):Eupteleasaponins I、II、III 的结构。IV、V 和 V
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Hisashi Matsuda el al.: "Possible Involvement of 5-HT_2 Receptors in Acceleration of Gastrointestinal Transit by Escin Ib in Mice"Life Sci.. 66. 2233-2238 (2000)
Hisashi Matsuda 等人:“小鼠中七叶皂苷 Ib 可能参与 5-HT_2 受体加速胃肠转运”Life Sci.. 66. 2233-2238 (2000)
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共 54 条
A classification study of Unique Forms and Usages of Chinese Characters
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财政年份:2013
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Search for protective compounds from Egyptian traditional medicines on metabolic syndrome
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A general study on the unclassified languages spoken in the southern Hunan province of China
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批准号:20401020
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财政年份:2008
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负责人:YOSHIKAWA Masayuki
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依托单位:
Development for preventive and therapeutic constituents on lifestyle diseases from spices
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批准号:19590024
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2007
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负责人:YOSHIKAWA Masayuki
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依托单位:
SEARCH FOR NEW ANTIDIABETOGENIC AND ANTI-OBESE SEED COMPOUNDS FROM THE TRADITIONAL EGYPTIAN MEDICINES
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批准号:16590023
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2004
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负责人:YOSHIKAWA Masayuki
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依托单位:
A Sociolinguistic Study on the Transition and Variation of Reading and Writing in Hong Kong.
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批准号:16320048
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.7万
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财政年份:2004
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负责人:YOSHIKAWA Masayuki
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依托单位:
SEARCH FOR ANTI-OBESE AND ANTIDIABETOGENIC PRINCIPLES FROM THE AYURUVEDIC NATURAL MEDICINES
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批准号:14572022
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.5万
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财政年份:2002
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负责人:YOSHIKAWA Masayuki
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依托单位:
Characterization of Hepatoprotective Compounds from Chinese Medicinal Herbs with Anti-alcoholic Activity
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批准号:10672010
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.92万
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财政年份:1998
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负责人:YOSHIKAWA Masayuki
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依托单位:
Search for Bioactive Compounds on the Basis of Characterization of Crude Drug Processings
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批准号:08672461
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.22万
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财政年份:1996
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负责人:YOSHIKAWA Masayuki
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依托单位:
Characterization of Alcohol-Absorption Inhibitors from Chinese Traditional Medicines with Anti-Alcoholic Activity
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批准号:07557292
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$1.34万
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财政年份:1995
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负责人:YOSHIKAWA Masayuki
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依托单位:
Search for Antiallergic and Antidiabetic Constituents from Oriental Medicinal Foodstuffs
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批准号:06672126
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.47万
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财政年份:1994
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负责人:YOSHIKAWA Masayuki
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依托单位:
Syntheses of Carbocyclic Analogs of Nucleoside and Bioactive Pseudo-Sugars from Carbohydrate
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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负责人:YOSHIKAWA Masayuki
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依托单位:
Chemical Studies on Crude Drug Processing
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批准号:61571001
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1986
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负责人:YOSHIKAWA Masayuki
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依托单位:
Establishment of Quality Evaluation Method for Crude Drugs by GC-MS
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批准号:60870077
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项目类别:Grant-in-Aid for Developmental Scientific Research
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资助金额:$3.84万
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财政年份:1985
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负责人:YOSHIKAWA Masayuki
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依托单位: