Construction of Drug-Discovering System by using Multiple Fluorescent Labels on Peptide Library

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A lot of researchers have been trying to discover peptides that bind onto specific cancer cells, however, without success. A major reason for the unsucceesful attempts may be that the discovery processes have been done under conditions far from the conditions inside the living body. The purpose of this project is to establish a novel screening process by using multiple fluorescent labels on peptide library. Putting a solution of the peptide library onto cancer cells and identifying those bound onto the cells with fluorescence spectroscopy, we found several cancer cell specific octapeptides.