Nanoseond Ultra-Rapid Freeze Quenching for Time-resolved Structural Biology
Nanoseond Ultra-Rapid Freeze Quenching for Time-resolved Structural Biology
批准号:
451906961
负责人:
Professor Dr. Harald Schwalbe
金额:
$0.0万
依托单位国家:
德国
项目类别:
New Instrumentation for Research
财政年份:
--
资助国家:
德国
项目状态:
未结题
起止时间:
中文摘要
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英文摘要
The application aims to develop instrumentation for the time-resolved studies of biochemical processes, yielding 3D molecular movies recorded with atomic resolution in real time. Application targets regular and custom-made equipment for pre-steady-state triggering, sampling, probing and detection, including optical, cryo-sedimentation and ultra-high vacuum systems, UHPLC sample delivery and the computation cluster upgrade. Such instrumentation will be essential for time-resolved structural biology, in particular solid state NMR and cryo-EM.
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会议论文
Structure, dynamics and kinetics of folding of G-quadruplex nucleic acids
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批准号:392117191
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项目类别:Research Grants
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资助金额:$0.0万
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财政年份:2017
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负责人:Professor Dr. Harald Schwalbe
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依托单位:
Effects of glycosylation on protein structure, function and dynamics
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批准号:347211955
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项目类别:Research Units
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资助金额:$0.0万
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财政年份:2017
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负责人:Professor Dr. Harald Schwalbe
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依托单位:
Dynamic basis of the molecular mechanism of nucleotide secondary messengers-sensing riboswitches by NMR spectroscopy
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批准号:314774469
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项目类别:Priority Programmes
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资助金额:$0.0万
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财政年份:2016
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负责人:Professor Dr. Harald Schwalbe
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依托单位:
Elucidation of the mechanism of aggregation of disease-associated single point mutants of the murine prion protein on the basis of time-resolved 2D NMR spectroscopy in combination with complementary kinetic methods
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批准号:169270524
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项目类别:Research Grants
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资助金额:$0.0万
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财政年份:2010
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负责人:Professor Dr. Harald Schwalbe
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依托单位:
Strukturelle Charakterisierung der human accelerated region 1 RNA vonMensch und Schimpansen
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批准号:151328194
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项目类别:Research Grants
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资助金额:$0.0万
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财政年份:2009
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负责人:Professor Dr. Harald Schwalbe
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依托单位:
NMR Investigation of the Regulation of Gene Expression by RNA Thermometers
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批准号:40116492
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项目类别:Priority Programmes
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资助金额:$0.0万
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财政年份:2007
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负责人:Professor Dr. Harald Schwalbe
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依托单位:
Improvement of the NMR structural quality for RNA and DNA
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批准号:537258662
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项目类别:Research Grants
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资助金额:$0.0万
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财政年份:--
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负责人:Professor Dr. Harald Schwalbe
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依托单位:
SARS-CoV-2-RNA: Understanding the RNA architecture of SARS-CoV-2
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批准号:495006306
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项目类别:Research Grants
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资助金额:$0.0万
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财政年份:--
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负责人:Professor Dr. Harald Schwalbe
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依托单位:
NMR and biophysical characterization of structure and dynamics of µ-proteins and their complexes.
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批准号:379644268
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项目类别:Priority Programmes
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资助金额:$0.0万
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财政年份:--
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负责人:Professor Dr. Harald Schwalbe
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依托单位:
Effects of glycosylation on protein structure, function and dynamics
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批准号:445098147
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项目类别:Research Units
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资助金额:$0.0万
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财政年份:--
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负责人:Professor Dr. Harald Schwalbe
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依托单位:
国内基金
海外基金
磷脂酶Ultra特异性催化油脂体系中微量磷脂分子的调控机制研究
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批准号:31471690
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项目类别:面上项目
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资助金额:90.0万元
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批准年份:2014
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负责人:王永华
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依托单位:
适应纳米尺度CMOS集成电路DFM的ULTRA模型完善和偏差模拟技术研究
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批准号:60976066
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项目类别:面上项目
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资助金额:41.0万元
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批准年份:2009
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负责人:何进
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依托单位: