Ultra-Rapid RF-Based Beam Monitor for Real-Time FLASH Beam Control

TibaRay开发了一种束流监测器，能够在单个线性加速器脉冲内解析纳秒级聚束结构。该速度使得脉冲间射束控制（在毫秒时间尺度上）容易实现，并且甚至产生脉冲内射束控制的可能性，即，在微秒时间尺度上测量和中断部分脉冲。我们现在已经设计和原型的下一阶段的集成这一概念，通过建立一个束流监测RF腔直接在6 MeV的FLASH电子直线加速器结构。 本提案的目的是验证我们的集成RF射束监测器在FLASH照射条件下的绝对电荷和绝对剂量的校准，并演示一个基本的闭环反馈系统，该系统能够根据检测到的信号在脉冲之间中断射束。通过这种验证，我们的方法将代表一个通用平台，用于确保FLASH RT在临床中的安全和稳健交付。

TibaRay has developed a beam monitor that is capable of resolving the nanosecond-scale bunch structure within individual linear accelerator pulses. This speed makes inter-pulse beam control (on the millisecond time scale) readily achievable, and even creates the possibility of intra-pulse beam control, i.e., measurement and interruption of partial pulses on the microsecond time scale. We have now designed and prototyped the next stage of integration of this concept, by building a beam monitoring RF cavity directly within a 6 MeV FLASH electron linear accelerator structure. The aims of this proposal are to validate the calibration of our integrated RF beam monitor for absolute charge and absolute dose under FLASH irradiation conditions, and to demonstrate a basic closed loop feedback system capable of interrupting the beam between pulses based on the detected signal. With this validation, our approach would represent a general platform for ensuring safe and robust delivery of FLASH RT in the clinic.