Ultra-Rapid RF-Based Beam Monitor for Real-Time FLASH Beam Control

用于实时闪光光束控制的基于射频的超快速光束监视器

• 批准号: 10714368
• 负责人: ARUNDHUTI GANGULY
• 金额: $ 39.96万
• 依托单位: TIBARAY, INC.
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-16 至 2023-09-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10714368
• 关键词: Calibration; Charge; Clinic; Collimator; Data; Dose; Electrons; Ensure; Feedback; Film; Height; Individual; Interruption; Ions; Linear Accelerator Radiotherapy Systems; Measurement; Monitor; Output; Physiologic pulse; Reproducibility; Signal Transduction; Solid; Speed; Structure; System; Testing; Time; Vacuum; Validation; Water; Width; base; beamline; design; irradiation; millisecond; nanosecond; prototype; real time monitoring

TibaRay has developed a beam monitor that is capable of resolving the nanosecond-scale bunch structure within individual linear accelerator pulses. This speed makes inter-pulse beam control (on the millisecond time scale) readily achievable, and even creates the possibility of intra-pulse beam control, i.e., measurement and interruption of partial pulses on the microsecond time scale. We have now designed and prototyped the next stage of integration of this concept, by building a beam monitoring RF cavity directly within a 6 MeV FLASH electron linear accelerator structure. The aims of this proposal are to validate the calibration of our integrated RF beam monitor for absolute charge and absolute dose under FLASH irradiation conditions, and to demonstrate a basic closed loop feedback system capable of interrupting the beam between pulses based on the detected signal. With this validation, our approach would represent a general platform for ensuring safe and robust delivery of FLASH RT in the clinic.

TibaRay开发了一种光束监测器，能够在单个线性加速器脉冲中分辨纳秒级束结构。这种速度使得脉冲间光束控制（毫秒时间尺度）很容易实现，甚至创造了脉冲内光束控制的可能性，即在微秒时间尺度上测量和中断部分脉冲。我们现在已经设计并原型化了这一概念的下一阶段集成，通过在6 MeV FLASH电子直线加速器结构中直接建立一个光束监测RF腔。