Ultra-Rapid RF-Based Beam Monitor for Real-Time FLASH Beam Control

TibaRay已经开发出一种束流监测器，能够分辨单个直线加速器脉冲内的纳秒尺度的束团结构。这种速度使得脉冲间波束控制(在毫秒时间尺度上)很容易实现，并且甚至创造了脉冲内波束控制的可能性，即在微秒时间尺度上测量和中断部分脉冲。我们现在已经设计并制作了这一概念的下一阶段集成的原型，通过在6 MeV闪光电子直线加速器结构中直接构建一个束流监控RF腔。 这项建议的目的是验证我们的集成射频束流监测器在闪光照射条件下对绝对电荷和绝对剂量的校准，并演示能够根据检测到的信号在脉冲之间中断束流的基本闭环反馈系统。有了这一验证，我们的方法将代表一个通用平台，以确保在临床上安全和可靠地提供闪光RT。

TibaRay has developed a beam monitor that is capable of resolving the nanosecond-scale bunch structure within individual linear accelerator pulses. This speed makes inter-pulse beam control (on the millisecond time scale) readily achievable, and even creates the possibility of intra-pulse beam control, i.e., measurement and interruption of partial pulses on the microsecond time scale. We have now designed and prototyped the next stage of integration of this concept, by building a beam monitoring RF cavity directly within a 6 MeV FLASH electron linear accelerator structure. The aims of this proposal are to validate the calibration of our integrated RF beam monitor for absolute charge and absolute dose under FLASH irradiation conditions, and to demonstrate a basic closed loop feedback system capable of interrupting the beam between pulses based on the detected signal. With this validation, our approach would represent a general platform for ensuring safe and robust delivery of FLASH RT in the clinic.