Effects of internet interventions for depression on suicide ideation – a meta-analysis of individual participant data (IPDMA).

互联网干预抑郁症对自杀意念的影响——个体参与者数据的荟萃分析（IPDMA）。

• 批准号: 453571562
• 负责人: Dr. Lasse Sander, Ph.D.
• 金额: --
• 依托单位: Abteilung für Medizinische Psychologie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/453571562?language=en
• 关键词: Effects; internet; interventions; depression; suicide

In recent years, a series of randomized controlled trials (RCTs) and meta-analyses have confirmed the efficacy of Internet-based self-help interventions for the treatment of depression. Based on these research results, the implementation of this new form of healthcare is currently ongoing in Germany. However, little is known about whether these procedures also have an impact (improvement and deterioration) on the suicidal ideation of patients. However, this information is crucial in the context of a widespread implementation of Internet-based treatment measures. At the same time, the complex interaction of depression and suicidal ideation is a general research desideratum of basic clinical-psychological research.The objectives of this study are therefore 1) to examine the effects of Internet-based interventions for depression on suicidal ideation and 2) to explore potential moderators, mediators and mechanisms of change in the interaction of depression and suicidal ideation.For this purpose, a meta-analysis based on individual participant data (IPD) of 62 RCTs and 14,088 participants will be performed. This complex methodological approach, coupled with the relatively high number of cases of RCTs in the field of Internet-based interventions, allows for the first time a detailed analysis of the complex interaction of depression and suicidal ideation.The study will thus make a significant contribution to basic clinical-psychological research, while providing insights equally relevant to researchers, practitioners and the healthcare policymakers. The ongoing and increasing implementation of Internet-based treatment of depression in Germany lends this research project additional relevance.

近年来，一系列随机对照试验(RCT)和荟萃分析证实了基于互联网的自助干预治疗抑郁症的有效性。根据这些研究结果，德国目前正在实施这种新形式的医疗保健。然而，关于这些程序是否也对患者的自杀意念有影响(改善和恶化)，我们知之甚少。然而，在广泛实施基于互联网的治疗措施的背景下，这一信息是至关重要的。同时，抑郁与自杀意念的复杂交互作用也是基础临床心理学研究的一个普遍研究方向。因此，本研究的目的是：1)考察基于互联网的抑郁干预对自杀意念的影响；2)探索抑郁与自杀意念交互作用的调节因素、中介变量和变化机制。这种复杂的方法方法，再加上基于互联网的干预领域相对较高的随机对照试验病例数量，首次允许详细分析抑郁症和自杀意念的复杂相互作用。因此，这项研究将对基础临床心理学研究做出重大贡献，同时提供与研究人员、从业者和医疗保健政策制定者同等相关的见解。德国正在进行并越来越多地实施基于互联网的抑郁症治疗，这增加了这一研究项目的相关性。