Development of a new therapy for xerostomia using mechanobiology
Development of a new therapy for xerostomia using mechanobiology
批准号:
23890195
负责人:
KONDO Yusuke
金额:
$2.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
我计划这项研究开发一种新的治疗口干症的方法,使用机械生物学结合毒蕈碱激动剂。结果表明,唾液腺功能具有温度敏感性,这与细胞内Ca 2+浓度增加有关。此外,还阐明了低渗环境下唾液分泌的更新,并提出了Na+-K+-2Cl转运体活性参与的原因。
英文摘要
I planned this study to develop a new therapy for xerostomia using mechanobiologycombined with muscarinic agonists. As a result, it was revealed that salivary gland function is temperature-sensitive, which is associated with intracellular Ca2+concentration increase. In addition, it is also clarified that the saliva secretion is updated in hypotonic environment, and the involvement of Na+-K+-2Clcotransporter activity has been suggested as the cause.
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DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[T Mukaibo, T Nakamoto, Y Kondo, M Kidokoro, A Imamura, C Masaki and R, 平田-土屋志津,寺下正道,岡本一起,北村知昭, TaroMukaibo, Tsuchiya-Hirata S, YusukeKondo, 平田-土屋志津, 平田志津, AtsusiImamura]
通讯作者:
AtsusiImamura
Hyperand hypo- osmolarity on submandibular glandfunction
高渗透压和低渗透压对颌下腺功能的影响
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[M Kidokoro, A Imamura, Y Kondo, T Mukaibo, C Masaki, R Hosokawa and T Nakamoto]
通讯作者:
R Hosokawa and T Nakamoto
Hosokawa, Thermal influence of saliva secretionex vivo in the mouse submandibular gland
Hosokawa,小鼠颌下腺离体唾液分泌的热影响
DOI:
--
发表时间:
2013
期刊:
Open Journal of Stomatology
影响因子:
--
作者:
[T Mukaibo, T Nakamoto, Y Kondo, M Kidokoro, A Imamura, C Masaki and R]
通讯作者:
C Masaki and R
Hyper- and hypo-osmolarity on submandibular gland function
高渗透压和低渗透压对颌下腺功能的影响
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Manami Kidokoro, Atsushi Imamura, Yusuke Kondo, Taro Mukaibo, Chihiro Masaki, Ryuji Hosokawa, Tetsuji Nakamoto]
通讯作者:
Tetsuji Nakamoto
DOI:
10.4236/ojst.2013.31015
发表时间:
2013
期刊:
Open Journal of Stomatology
影响因子:
--
作者:
[T Mukaibo, T Nakamoto, Y Kondo, M Kidokoro, A Imamura, C Masaki and R, 平田-土屋志津,寺下正道,岡本一起,北村知昭, TaroMukaibo]
通讯作者:
TaroMukaibo
共 6 条
Analysis of TrkB and BDNF expression and function in malignant salivary gland tumors
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批准号:16K19089
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.58万
-
财政年份:2016
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负责人:KONDO Yusuke
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依托单位:
Research on formation of the Shugendo organization, and local deployment
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批准号:23720326
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$0.92万
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财政年份:2011
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负责人:KONDO Yusuke
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依托单位:
The development of an automated scoring system for English learners' speech in discourse completion task and its evaluation
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批准号:23520721
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2011
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负责人:KONDO Yusuke
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依托单位:
The development and the evaluation of automatic speech scoring system for learners of English
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批准号:21720209
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.0万
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财政年份:2009
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负责人:KONDO Yusuke
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依托单位:
A study of prosody of second language learner of English in Reading aloud: Educational measurement by Item Response Theory and acoustic analysis
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批准号:19720145
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.25万
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财政年份:2007
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负责人:KONDO Yusuke
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依托单位:
海外基金