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Development of a new therapy for xerostomia using mechanobiology

Development of a new therapy for xerostomia using mechanobiology
利用机械生物学开发口干症新疗法
批准号:
23890195
负责人:
KONDO Yusuke
金额:
$2.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

项目摘要

项目成果

KONDO Yusuke的其他基金

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相关文献

中文摘要
翻译
我计划这项研究开发一种新的治疗口干症的方法,使用机械生物学结合毒蕈碱激动剂。结果表明,唾液腺功能具有温度敏感性,这与细胞内Ca 2+浓度增加有关。此外,还阐明了低渗环境下唾液分泌的更新,并提出了Na+-K+-2Cl转运体活性参与的原因。
英文摘要
I planned this study to develop a new therapy for xerostomia using mechanobiologycombined with muscarinic agonists. As a result, it was revealed that salivary gland function is temperature-sensitive, which is associated with intracellular Ca2+concentration increase. In addition, it is also clarified that the saliva secretion is updated in hypotonic environment, and the involvement of Na+-K+-2Clcotransporter activity has been suggested as the cause.
期刊论文(7)
专著(0)
科研奖励(0)
会议论文
Tannic acid inhibits salivation from ex vivo mouse submandibular glands
单宁酸抑制离体小鼠颌下腺分泌唾液
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [T Mukaibo, T Nakamoto, Y Kondo, M Kidokoro, A Imamura, C Masaki and R, 平田-土屋志津,寺下正道,岡本一起,北村知昭, TaroMukaibo, Tsuchiya-Hirata S, YusukeKondo, 平田-土屋志津, 平田志津, AtsusiImamura]
通讯作者: AtsusiImamura
Hyperand hypo- osmolarity on submandibular glandfunction
高渗透压和低渗透压对颌下腺功能的影响
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [M Kidokoro, A Imamura, Y Kondo, T Mukaibo, C Masaki, R Hosokawa and T Nakamoto]
通讯作者: R Hosokawa and T Nakamoto
Hosokawa, Thermal influence of saliva secretionex vivo in the mouse submandibular gland
Hosokawa,小鼠颌下腺离体唾液分泌的热影响
DOI: --
发表时间: 2013
期刊: Open Journal of Stomatology
影响因子: --
作者: [T Mukaibo, T Nakamoto, Y Kondo, M Kidokoro, A Imamura, C Masaki and R]
通讯作者: C Masaki and R
Hyper- and hypo-osmolarity on submandibular gland function
高渗透压和低渗透压对颌下腺功能的影响
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Manami Kidokoro, Atsushi Imamura, Yusuke Kondo, Taro Mukaibo, Chihiro Masaki, Ryuji Hosokawa, Tetsuji Nakamoto]
通讯作者: Tetsuji Nakamoto
共 6 条
    Analysis of TrkB and BDNF expression and function in malignant salivary gland tumors
    • 批准号:
      16K19089
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.58万
    • 财政年份:
      2016
    • 负责人:
      KONDO Yusuke
    • 依托单位:
    Research on formation of the Shugendo organization, and local deployment
    • 批准号:
      23720326
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $0.92万
    • 财政年份:
      2011
    • 负责人:
      KONDO Yusuke
    • 依托单位:
    The development of an automated scoring system for English learners' speech in discourse completion task and its evaluation
    • 批准号:
      23520721
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2011
    • 负责人:
      KONDO Yusuke
    • 依托单位:
    The development and the evaluation of automatic speech scoring system for learners of English
    • 批准号:
      21720209
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $1.0万
    • 财政年份:
      2009
    • 负责人:
      KONDO Yusuke
    • 依托单位:
    海外基金