课题基金 / 基金详情

Development of the novel biomarker for tissue damage using polyamines and their metabolites

Development of the novel biomarker for tissue damage using polyamines and their metabolites
使用多胺及其代谢物开发组织损伤的新型生物标志物
批准号:
24890195
负责人:
UEMURA Takeshi
金额:
$1.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-08-31 至 2014-03-31

项目摘要

项目成果

UEMURA Takeshi的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
The objective of this research is to develop a novel test for the identification of the cause of death in legal autopsy cases. We found that alcohol consumption induced spermine oxidase (SMO) at the transcriptional level in the liver and generated acrolein by polyamine metabolism to exert cytotoxicity. Our results indicate that polyamines and acrolein levels in liver tissues can be used as a novel biomarker for tissue damage caused by alcohol consumption.
期刊论文(12)
专著(0)
科研奖励(0)
会议论文
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Matsuda M, Tsurumi-Ikeya Y, et al., Yukihiro Itoh, 砂川陽一, 植村武史,高坂友和,宮森大輔,吉本寛司,池谷 博]
通讯作者: 植村武史,高坂友和,宮森大輔,吉本寛司,池谷 博
京都府立医科大学法医学教室
京都府立医科大学法医学系
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
Acetaldehyde-induced cytoxicity involves induction of spermine oxidase at the transcrptional level
乙醛诱导的细胞毒性涉及转录水平上精胺氧化酶的诱导
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Uemura T, Tanaka Y, Higashi K, Miyamori D, Takasaka T, Nagano T, Toida T, Yoshimoto K, Igarashi K, and Ikegaya H]
通讯作者: and Ikegaya H
Regulation of cellular polyamines by transport, protein sorting and metabolism
通过运输、蛋白质分选和代谢调节细胞多胺
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Uemura T, Stringer DE, Blohm-Mangone KA, Ikegaya H, Gerner EW]
通讯作者: Gerner EW
10
    Advanced technology development for analyzing molecular dynamics and structure in synapse formation
    • 批准号:
      26640039
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.5万
    • 财政年份:
      2014
    • 负责人:
      UEMURA Takeshi
    • 依托单位:
    Study on molecular mechanism of cerebellar circuit formation
    • 批准号:
      25290021
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.82万
    • 财政年份:
      2013
    • 负责人:
      UEMURA Takeshi
    • 依托单位:
    New Development of surgical techniques at tissue transfer - application of synthetic double-stranded oligodeoxynucleotide -
    • 批准号:
      23792041
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.75万
    • 财政年份:
      2011
    • 负责人:
      UEMURA Takeshi
    • 依托单位:
    Study on molecular mechanisms of synapse formation by glutamate receptor(GluR)δ2
    • 批准号:
      22700390
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.58万
    • 财政年份:
      2010
    • 负责人:
      UEMURA Takeshi
    • 依托单位:
    海外基金