Comparison of endrine disruption activities of urban wastewater by reporter gene assay considering difference in speices sensitivities
Comparison of endrine disruption activities of urban wastewater by reporter gene assay considering difference in speices sensitivities
批准号:
23254003
负责人:
TANAKA Hiroaki
金额:
$34.03万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011-04-01 至 2014-03-31
中文摘要
通过实地调查,比较了日本、英国、中国和韩国污水覆盖率不同的污水、处理后的污水和接收水中的生物活性物质和化合物,如药物、个人护理产品以及雌激素。收集流域信息,模拟生物活性化合物在河流转化过程中的归宿,以估计其来源并预测流域未来的趋势。此外,采用来自不同鱼类和人类的雌激素受体的报告基因测定适用于实验性水样。 在英国,中国和韩国收集的样品进行了测量与开发的检测。
英文摘要
Bioactive activities and compounds such as pharmaceuticals, personal care products as well as estrogens of sewage, treated sewage, and receiving water were compared among Japan, United Kingdom, China and Korea whose sewerage coverage levels are diffrent through field surveys . River basin information was collected and the fates of the bioactive compounds in river trnsformation process were modeled to estimate their sources and to predict future trends of the river basins. Further, reporter gene assays emplolying estrogen recepters derived from diffrent fish speices and human were adapted to enmvironmental water samples. The samples collected in the UK, China and Korea were measured with the developed assay.
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淀川水系における抗がん剤成分の挙動把握
了解淀川水系统中抗癌药物成分的行为
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Ihara M, Lee S, Katakawa Y, Yamashita N, Matsuda T, Tanaka H, 花本征也,中田典秀,山下尚之,田中宏明, 東剛志,井ノ山智美,寺西裕亮,石打浩隆,山岡美里,三野芳紀,中田典秀,山下尚之,田中宏明]
通讯作者:
東剛志,井ノ山智美,寺西裕亮,石打浩隆,山岡美里,三野芳紀,中田典秀,山下尚之,田中宏明
Evaluation on endocrine disrupting activity and interspecies sensitivies of wastewater samples using the reporter gene assay derived from different organism
使用来自不同生物体的报告基因测定评估废水样品的内分泌干扰活性和种间敏感性
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Mariko Ohno, Masaru Ihara, Vimal Kumar, Masanori Narumiya, Seiya Hanamoto, Shinichi Miyagawa, Taisen Iguchi, Hiroaki Tanaka]
通讯作者:
Hiroaki Tanaka
The Basic Consideration for Identification of Anti-estrogenic Chemicals in Wastewater
废水中抗雌激素化学物质鉴定的基本考虑
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Ohno M]
通讯作者:
Ohno M
京都大学-清華大学環境技術共同研究・教育センター
京都大学-清华大学环境技术联合研究教育中心
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
下水中の抗エストロゲン物質同定のための基礎検討
污水中抗雌激素物质鉴定的基础研究
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Aiba, S., Akutsu, K., 大野満里子]
通讯作者:
大野満里子
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Enhancing low-motivated learners: From the viewpoint of individual differences
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Evaluation and Control of Water Pollution due to Residual Pharmaceuticals Suspected High Risk on Aquatic Ecosystems
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Impact of TGFbeta Inhibitor on dendritic cells and vaccine therapy for gastric cancer
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