PHYSIOLOGICAL CHARACTERISTICS OF HIGH-ALTITUDE ADAPTED ANIMALS
高海拔动物的生理特征
基本信息
- 批准号:12576001
- 负责人:
- 金额:$ 8.7万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (B)
- 财政年份:2000
- 资助国家:日本
- 起止时间:2000 至 2002
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The blue sheep as well as pika, and yak live in the Tibetan highlands to an altitude of 6,100 m and are typical animals adapted to high altitude among mammals of the world. These animals have a long history of habitation at high altitude and are considered to be "animals completely adapted to high altitude" because of their physiologic and morphological traits well-adapted to high-altitude environments. To evaluate physiologic characteristics of high-altitude adaptation of the blue sheep, changes in the pulmonary hemodynamics were examined in Qinghai Province, China (altitude 3,750 m). Primary items of measurement were the body weight (BW), systemic arterial pressure (Psa), pulmonary artery pressure (Ppa), hematocrit (Ht), left ventricular weight (LVW), right ventricular weight (RVW), and the blood gas profile. The principal finding of this study are: 1) Ht, at index of right ventricular hypertrophy (RVW/LVW), and oxygen consumption (VO2) were significantly smaller in the blue sheep compared with the pigs; 2) Ppa/Psa, an index of the right ventricular load, increased with the altitude in both species, but the increases were smaller in the blue sheep. From these observations, small Ht and RVW/LVW are considered to be characteristics of animals completely adapted to high altitude such as the pika.
蓝羊、鼠兔和牦牛生活在海拔6100米的西藏高原,是世界哺乳动物中适应高海拔的典型动物。这些动物在高海拔地区居住的历史很长,由于它们的生理和形态特征很好地适应了高海拔环境,被认为是“完全适应高海拔地区的动物”。为探讨青海蓝羊高原适应的生理特点,对海拔3750m的青海省中国羊进行了肺血流动力学的测定。主要测量指标为体重(BW)、体动脉压(PSA)、肺动脉压(PPA)、红细胞压积(Ht)、左室重(LVW)、右室重(RVW)和血气分析。本研究的主要发现是:1)与猪相比,蓝羊的右室肥厚指数(RVW/LVW)和氧耗量(VO2)显著减小;2)两种羊的右室负荷指标PPA/PSA均随海拔升高而增加,但蓝羊的增加幅度较小。根据这些观察,小Ht和RVW/LVW被认为是完全适应高海拔动物的特征,如鼠兔。
项目成果
期刊论文数量(4)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
酒井 秋男 他: "チベットヒツジの高地順応特性"環境科学年報. 24. 87-98 (2002)
Akio Sakai等:“藏羊的高海拔驯化特征”环境科学年报24。87-98(2002)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
酒井秋男 他: "チベットヒツジの高地順応特性"環境科学年報. 24. 87-98 (2002)
Akio Sakai等:“藏羊的高海拔驯化特征”环境科学年报24。87-98(2002)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
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SAKAI Akio其他文献
SAKAI Akio的其他文献
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{{ truncateString('SAKAI Akio', 18)}}的其他基金
Intellectual Property Rights as an International Public Good and the Frontiers of Patent Competition
知识产权作为国际公共物品与专利竞争的前沿
- 批准号:
13630053 - 财政年份:2001
- 资助金额:
$ 8.7万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Development of a new instrument for non-invasive measurements of tissue (muscle) blood flow by near-infrared spectoroscopy.
开发一种通过近红外光谱法无创测量组织(肌肉)血流的新仪器。
- 批准号:
11670063 - 财政年份:1999
- 资助金额:
$ 8.7万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Development and application of a method for non-invasive measurements of local oxygen consumption by near-infrared spectroscopy
近红外光谱无创测量局部耗氧量方法的开发与应用
- 批准号:
07557007 - 财政年份:1995
- 资助金额:
$ 8.7万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
Nature of IPE from a Viewpoint of Economics and Scenarios of World Order in the Post-Cold War Era
从经济视角和冷战后世界秩序情景看IPE的本质
- 批准号:
07630037 - 财政年份:1995
- 资助金额:
$ 8.7万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Japan-U.S.Dispute over Intellectual Property Rights and its Impact on Link-up between Firms and Policy Coordination
日美知识产权争端及其对企业对接和政策协调的影响
- 批准号:
04630028 - 财政年份:1992
- 资助金额:
$ 8.7万 - 项目类别:
Grant-in-Aid for General Scientific Research (C)
Research on High-altitude Adapted Animal Models
高海拔适应动物模型研究
- 批准号:
04454577 - 财政年份:1992
- 资助金额:
$ 8.7万 - 项目类别:
Grant-in-Aid for General Scientific Research (B)
Mechanisms of Adaptation to High-altitude on Pulmonary Circulation.
高海拔对肺循环的适应机制。
- 批准号:
01480133 - 财政年份:1989
- 资助金额:
$ 8.7万 - 项目类别:
Grant-in-Aid for General Scientific Research (B)
Adaptation to high-altitude
适应高海拔
- 批准号:
62480113 - 财政年份:1987
- 资助金额:
$ 8.7万 - 项目类别:
Grant-in-Aid for General Scientific Research (B)
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