Super-Magnification Radiography Using Micro-Focus Fluorescent X-rays Generated by Synchrotron Radiation

使用同步加速器辐射产生的微焦点荧光 X 射线进行超放大射线照相

• 批准号: 13470186
• 负责人: TOYOFUKU Fukai
• 金额: $ 9.09万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-13470186/
• 关键词: synvhrotron radiation; fluorescent x-ray; magnifivation radiography; mammography; マンモグラフィ; 単色X線

The high spatial resolution requirements of x-ray imaging such as mammography demand the use of very small focal spots. We have developed a micro-focus fluorescent x-ray source with a focal spot size of 0.05 to 0.01mm for magnification imaging using a 6.5 GeV synchrotron radiation(SR) storage ring at Tsukuba(Japan). The micro-focus fluorescent x-ray source is composed of a collimator system and a target box. The incident white x-ray beam from the bending magnet irradiates a metal target and fluorescent x-rays are extracted to the transverse directions. The beam was collimated by using two slit collimators which were adjusted by the motorized stages. The effective focal spot size of 0.05,0.02,and 0.01mm^2 was obtained by changing the width of the slits. Fluorescent x-rays, which range from about 8keV to 68keV were generated by changing the target materials.Energy spectra of the fluorescent x-rays were measured by using a CdTe detector. In case of the Mo target, K_a, (17.5keV) and K_b(19.6keV) fluorescent x-rays were dominant, and the Compton scattered x-rays were almost negligible. The modulation transfer function(MTF) was also measured using the edge method. In the measurement, a 4x magnified edge image was taken using a non-screen dental x-ray film. Magnification radiography was performed by using non-screen films and imaging plates(IPs). The magnified images of the phantoms, such as CDMAM and other phantoms with simulated microcalsifications, show the potential applications of the present method to high resolution mammographyThe micro-focus fluorescent x-ray source using SR proved to be useful for high resolution magnification imaging

X射线成像（例如乳房X线摄影）的高空间分辨率要求需要使用非常小的焦斑。我们已经开发了一个微焦点荧光X射线源的焦斑尺寸为0.05至0.01毫米的放大成像使用6.5 GeV的同步辐射（SR）存储环在筑波（日本）。微焦点荧光X射线源由准直系统和靶盒组成。来自弯曲磁体的入射白色x射线束照射金属靶，并沿横向提取荧光x射线。光束通过使用两个狭缝准直器进行准直，所述狭缝准直器由电动载物台调节。通过改变狭缝的宽度，得到了0.05、0.02和0.01mm^2的有效焦斑尺寸。通过改变靶材料产生了能量范围为8 ~ 68 keV的荧光X射线，用CdTe探测器测量了荧光X射线的能谱。在Mo靶的情况下，K_a（17.5keV）和K_B（19.6keV）荧光X射线占优势，康普顿散射X射线几乎可以忽略。还使用边缘法测量了调制传递函数（MTF）。在测量中，使用无屏牙科X射线胶片拍摄4倍放大的边缘图像。使用无屏胶片和成像板（IP）进行放大X线摄影。对CDMAM和其他模拟微钙化的体模的放大图像显示了本方法在高分辨率乳腺X线摄影中的潜在应用

项目成果

F.Toyofuku, Y.Higashida, et al.: "Super-Magnification Imaging Using Micro-Focus Fluorescent X-rays"J.J.Med.Phys.. 57-58 (2004)

F.Toyofuku、Y.Higashida 等：“使用微焦点荧光 X 射线的超放大成像”J.J.Med.Phys.. 57-58 (2004)

坂本弘巳 他: "K-エッジフィルタを組み合わせた胸部X線撮影 -実験およびモンテカルロシミュレーションを用いた研究-"久留米医学会雑誌. 64巻・9-12号. 285-294 (2001)

Hiromi Sakamoto 等人：“结合 K 边缘滤波器的胸部 X 射线成像 - 使用实验和蒙特卡洛模拟进行的研究”Kurume Medical Society Journal，第 64 卷，第 285-294 期（2001 年）。

豊福不可依, 東田善治, 徳森謙二, 他: "微小焦点蛍光X線による超拡大撮影"医学物理. 24 Sup.2. 57-58 (2004)

Ikei Toyofuku、Yoshiharu Higashida、Kenji Tokumori 等人：“使用微焦点荧光 X 射线的超放大成像”医学物理学 24 Sup.2 (2004)。

高木理恵, 東田善治, 坂本祐二, 他: "アモルファスシリコンを検出器に用いたフルデジタルマンモグラフィシステム"日本乳癌検診学会雑誌. 13. 88-96 (2004)

Rie Takagi、Yoshiharu Higashida、Yuji Sakamoto 等：“使用非晶硅作为检测器的全数字乳房 X 线摄影系统”日本乳腺癌筛查协会杂志 13. 88-96 (2004)。

F.Toyofuku et al.: "Comparis on of parallel and fan-beam monochromatic X-ray CT using Synchrotron Radiation"Proc. of the 3^<rd> Korea-Japan Joint Meeting on Medical Physics. 407-410 (2002)

F.Toyofuku 等人：“使用同步辐射的平行和扇束单色 X 射线 CT 的比较”Proc。