Basic research for wavefront-guided refractive surgery : The evaluation of effects of aberrations and scatterings on the optical function of the eye

波前引导屈光手术的基础研究：像差和散射对眼睛光学功能影响的评估

• 批准号: 15591854
• 负责人: MAEDA Naoyuki
• 金额: $ 2.24万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15591854/
• 关键词: wavefront technology; refractive surgery; aberration; scattering; visual function; irregular astigmatism; wavefront sensor; excimer laser

As one of the cause of post-operative complications, the mechanism of transient keratectasia in association with a marked intraocular pressure (IOP) elevation was shown.Monocular triplopia was reported by middle-aged patients with mild nuclear cataract and high myopia. Wavefront analyses suggested that the triple configuration was caused by the combined increase of the trefoil and spherical aberration in lenses with nuclear cataract.The transplantation of tissue-engineered epithelial cell sheets can successfully prevent the development of corneal haze after excimer laser keratectomy.The tear break-up time measured by Hartmann-Shack aberrometer may be used as a practical measure of tear break-up.

作为术后并发症的原因之一，显示了与眼内压（IOP）升高相关的短暂性角膜干酪症的机制。据报道，中年性核白内障和高近视的中年患者据报道单眼三局部。波前分析表明，三重构型是由核白内障的透镜中的三叶和球形像差的综合增加引起的。组织工程工程的上皮细胞表的移植能够成功地防止在泪液中撕裂时撕裂时，可以成功地防止角膜雾化的形成型撕裂时，以指出撕裂的时间。

项目成果

Hitoshi Hayashi: "Sclerotic scattering illumination during phototherapeutic keratectomy for better visualization of corneal opacity"Am J Ophthalmol. 135. 559-561 (2003)

Hitoshi Hayashi：“光疗角膜切除术期间的硬化散射照明，可更好地显示角膜混浊”Am J Ophthalmol。

Transient keratectasia caused by intraocular pressure elevation after laser in situ keratomileusis.

• DOI: 10.1016/j.jcrs.2004.08.046
• 发表时间: 2005
• 期刊: Journal of cataract and refractive surgery
• 影响因子: 2.8
• 作者: A. Toshino;T. Uno;Y. Ohashi;N. Maeda;T. Oshika

Sayuri Ninomiya: "Wavefront analysis in eyes with acommodative spasm"Am J Ophthalmol. 136. 1161-1163 (2003)

Sayuri Ninomiya：“调节性痉挛眼睛的波前分析”Am J Ophamol。

Wavefront analysis of eyes with cataracts in patients with monocular triplopia

• DOI: 10.1111/j.1475-1313.2005.00352.x
• 发表时间: 2006-01-01
• 期刊: OPHTHALMIC AND PHYSIOLOGICAL OPTICS
• 影响因子: 2.9
• 作者: Kim, A;Bessho, K;Fujikado, T
• 通讯作者: Fujikado, T

Tear film break-up time evaluated by real-time Hartmann-Shack wavefront sensing

• DOI: 10.1007/s10384-005-0289-6
• 发表时间: 2006-03-01
• 期刊: JAPANESE JOURNAL OF OPHTHALMOLOGY
• 影响因子: 2.4
• 作者: Mihashi, T;Hirohara, Y;Fujikado, T
• 通讯作者: Fujikado, T