Study about the effects of footbath on immune functions and autonomic nervous system and its usefulness.

足浴对免疫功能和自主神经系统的影响及其用途的研究。

基本信息

项目摘要

Objectives : Footbath has long been used for the relief of fatigue, common cold and minor symptoms and it has been known that footbath can influence human body and the mind. This study was designed to investigate the effect of footbath on autonomic nerve and immune functions.Methods : Ten healthy female subjects (21-24 years of age) volunteered to participate in the present study. They experienced three different tests on the three different days ; only sitting without soaking their feet (Control), a footbath with soaking their feet in hot water at 42℃ (FB), and a footbath with soaking their feet in hot water at 42℃ with air-bubble and vibration given to the sole of the feet (B+V) for 10 min. Autonomic functions were evaluated by measuring electrocardiogram (ECG) and skin blood flow (BF) of sural region and spectral analysis of heart rate variability. As immune function, leukocytes subsets and lymphocytes subsets were measured three times ; before, immediately and at 60 min after footbath, using flow cytometric analysis. Cytotoxicity of natural killer (NK) cells against K562 was determined by europium-release assay.Results and Discussion : BF increased significantly during B+V, but returned to the before level immediately after the end of the footbath. In spectral analysis, high frequency component (HFC) increased and a ratio of low frequency component (LFC)/HFC decreased following usual footbath or B+V, indicating increased parasympathetic and decreased sympathetic nervous systems. A number of lymphocytes and NK cells cytotoxicity increased significantly after B+V. These results suggested that footbath might induce physiological relaxed condition in autonomic nervous system. Furthermore, footbath with air-bubble and vibration increased NK cells cytotoxicity according to an increase in parasympathetic nervous system. We thought that footbath with mechanical stimulation would be an efficacious method in physical improvement.
目的:洗脚长期以来一直用于缓解疲劳,普通感冒和轻微症状,并且人们已经知道洗脚可以影响人体和精神。本研究旨在探讨足浴对植物神经和免疫功能的影响。方法:10名健康女性志愿者(21-24岁)参加本研究。在三天的时间里,他们经历了三次不同的考验。只坐着不泡脚(对照组),用42℃热水泡脚(FB),用42℃热水泡脚,足底气泡振动(B+V)10 min,测定心电图(ECG),评价自主神经功能。腓肠区皮肤血流量(BF)和心率变异性的频谱分析。作为免疫功能,白细胞亚群和淋巴细胞亚群测定三次;前,立即和后60分钟,用流式细胞仪分析。结果与讨论:B+V期间BF显著增加,但浴足结束后立即恢复至浴前水平。在频谱分析中,高频成分(HFC)增加,低频成分(LFC)/HFC的比值降低后,通常洗脚或B+V,表明增加副交感神经系统和减少交感神经系统。B+ V后,外周血淋巴细胞和NK细胞的杀伤活性明显升高。提示足浴可引起植物神经系统的生理性放松状态。此外,气泡和振动足浴增加NK细胞的细胞毒性,根据副交感神经系统的增加。认为机械刺激足浴是一种有效的强身健体方法。

项目成果

期刊论文数量(20)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Effect of foot-bath with bubble and vibration on autonomic and immune functions.
气泡和振动足浴对植物神经和免疫功能的影响。
Effects of Footbath on Autonomic Nervous System, Leukocyte Subsets Natural Killer Cell Cytotoxicity.
足浴对自主神经系统、白细胞亚群自然杀伤细胞细胞毒性的影响。
Effects of somatic stimulation applied to feet on autonomic and immune functions.
足部躯体刺激对自主神经和免疫功能的影响。
Effects of Footbath on Autonomic Nervous System, Leukocyte Subsets and Natural Killer Cell Cytotoxicity.
足浴对自主神经系统、白细胞亚群和自然杀伤细胞细胞毒性的影响。
自律神経・免疫機能に及ぼす足への体性感覚刺激の効果
足部体感刺激对植物神经及免疫功能的影响
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NAGAI Nobuo其他文献

NAGAI Nobuo的其他文献

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{{ truncateString('NAGAI Nobuo', 18)}}的其他基金

Quantitative analysis of the roles of fibrinolysis system component on the vascular permeability after ischemic stroke by using new animal model
利用新动物模型定量分析纤溶系统成分对缺血性脑卒中后血管通透性的作用
  • 批准号:
    24590288
  • 财政年份:
    2012
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    $ 1.54万
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    Grant-in-Aid for Scientific Research (C)
Analysis of human body odor components adhered to clothes, and the influence which an unpleasant odor has on comfortable sensation.
分析衣服上附着的人体气味成分,以及难闻气味对舒适感的影响。
  • 批准号:
    23300266
  • 财政年份:
    2011
  • 资助金额:
    $ 1.54万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Roles of urokinase plasminogen activator receptor expressed in endothelial cells on deterioration of ischemic stroke
内皮细胞表达的尿激酶纤溶酶原激活剂受体在缺血性脑卒中恶化中的作用
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    21590244
  • 财政年份:
    2009
  • 资助金额:
    $ 1.54万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Application of Circuit Theory to Synthesis of New Materials Using Quantum Effect
电路理论在量子效应新材料合成中的应用
  • 批准号:
    05650321
  • 财政年份:
    1993
  • 资助金额:
    $ 1.54万
  • 项目类别:
    Grant-in-Aid for General Scientific Research (C)
A Study on Auto-Regressive and Moving-Average Lattice Digital Filters
自回归和移动平均格子数字滤波器的研究
  • 批准号:
    60550241
  • 财政年份:
    1985
  • 资助金额:
    $ 1.54万
  • 项目类别:
    Grant-in-Aid for General Scientific Research (C)

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