Synthesis of carbohydrate antigens and production of monoclonal antibodies for biotechnological applications

植物蛋白聚糖作为乳化剂和增稠剂广泛应用于澳大利亚农业食品工业。在植物中，它们参与了胚胎发生、发育和程序性细胞死亡等关键作用；最终决定农业生产的过程。然而，由于缺乏特异性试剂来探测植物蛋白聚糖的细胞功能，对植物蛋白聚糖的研究受到限制。我们建议开发一系列单克隆抗体，用于研究植物蛋白多糖的结构和功能。这些抗体将在基础和战略研究项目中有广泛的用途，并将加速用于食品工业的植物蛋白聚糖的商业发展。

Plant proteoglycans are widely used in the Australian agrifood industry as emulsifiers and thickening agents. In plants, they have been implicated in critical roles such as embryogenesis, development and programmed cell death; processes that ultimately determine agricultural production. However studies into plant proteoglycans are limited by a lack of specific reagents to probe their cellular function. We propose to develop a series of monoclonal antibodies that can be used to study the structure and function of plant proteoglycans. These antibodies will have broad uses in basic and strategic research programs and will accelerate the commercial development of plant proteoglycans for use in the food industry.