Dissecting catalysis and inhibition of a unique endo-acting mannose-processing glycosidase
Dissecting catalysis and inhibition of a unique endo-acting mannose-processing glycosidase
批准号:
DP120101396
负责人:
Prof Spencer Williams
金额:
$25.83万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-04-01 至 2015-03-31
中文摘要
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英文摘要
Defects in the attachment of carbohydrates to proteins are a hallmark of diseases such as cancer and viral infection. This project will dissect the molecular details of the bond-making and breaking steps that occur during the synthesis of glycoproteins assisting in the development of innovative new drugs.
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