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Large-scale knowledge information processing in genome analysis

Large-scale knowledge information processing in genome analysis
基因组分析中的大规模知识信息处理
批准号:
04261102
负责人:
KANEHISA Minoru
金额:
$107.52万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research on Priority Areas
财政年份:
1991
资助国家:
日本
项目状态:
已结题
起止时间:
1991 至 1995

项目摘要

项目成果

KANEHISA Minoru的其他基金

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中文摘要
翻译
优先领域“基因组信息学”的科学研究项目旨在为人类和其他生物的基因组研究开发新的计算技术。特别是,该项目重点解决了(I)如何组织和整合基因组分析产生的不同类型的数据的数据库问题,以及(Ii)如何破译编码在序列数据中的生物含义的计算问题,这是通过实验得出的最终产品。在五年的时间里,除了三卷的基因组信息学系列论文集外,我们还发表了100多篇原创论文。我们还出版了一批日语原创和评论论文、文件、小册子和书籍。该项目有助于建立GenomeNet计算机网络,作为日本生物医学研究的信息基础设施,并通过定期组织讲习班和教程培养生物信息学研究界。基础研究成果,特别是关于数据库问题的基础研究成果,已作为实用的数据库和软件产品在国际上作为GenomeNet数据库服务的一部分提供。
英文摘要
The Scientific Research Project on the Priority Area "Genome Informatics" aimed at developing new computational technologies for genome research on human and other organisms. Especially, the project focused on (i) the database problem of how to organize and integrate different types of data being produced by genome analyzes and (ii) the computational problem of how to decipher biological meaning encoded in the sequence data which is the final product by experiments. During the five year period, we published more than 100 original papers in addition to the three volumes of the Genome Informatics Series Proceedings. We also published a number of original and review papers, ducuments, pamphlets, and books in Japanese. The project has been instrumental in establishing the GenomeNet computer network as the informatics infrastructure for biomedical research in Japan and in nurturing the bioinformatics research community by regularly organizing workshops and tutorials. The basic research results, especially for the database problem, have been implemented as practical databases and software products that are internationally made available as a part of the GenomeNet database service.
期刊论文(62)
专著(0)
科研奖励(0)
会议论文
Hagiya,M.,Miyano,S.,Nakai,K.,Suyama,A.,Yokomori,T.,Takagi,T.: "Proceedings of Genome Informatics Workshop 1995" Universal Academy Press,Inc., 179 (1995)
Hagiya,M.、Miyano,S.、Nakai,K.、Suyama,A.、Yokomori,T.、Takagi,T.:“1995 年基因组信息学研讨会论文集”Universal Academy Press, Inc.,179(1995)
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通讯作者:
Ishikawa,M.,Toya,T.,Hoshida,M.,Nitta,K.,Ogiwara,A.,Kanehisa,M.: "Multiple sequence alignment by parallel simulated annealing." CABIOS. 9. 267-273 (1993)
Ishikawa,M.、Toya,T.、Hoshida,M.、Nitta,K.、Ogiwara,A.、Kanehisa,M.:“通过并行模拟退火进行多序列比对。”
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通讯作者:
Ogata,H.,Akiyama,Y.,Kanehisa,M.: "A genetic algorithm based molecular modeling technique for RNA stem-loop structures." Nucleic Acids Res.23. 419-426 (1995)
Ogata,H.、Akiyama,Y.、Kanehisa,M.:“基于遗传算法的 RNA 茎环结构分子建模技术。”
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通讯作者:
Tomii,K.,Kanehisa,M.: "Analysis of amino acid indices and mutation matrices for sequence comparison and structure prediction of proteins." Protein Eng.(in press). (1996)
Tomii,K.,Kanehisa,M.:“用于蛋白质序列比较和结构预测的氨基酸指数和突变矩阵分析。”
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29
    Backbone Database for Understanding the Biological Systems
    • 批准号:
      17020005
    • 项目类别:
      Grant-in-Aid for Scientific Research on Priority Areas
    • 资助金额:
      $227.9万
    • 财政年份:
      2005
    • 负责人:
      KANEHISA Minoru
    • 依托单位:
    Integrated Database of Microbial Genomes and Cellular Functions
    • 批准号:
      15013227
    • 项目类别:
      Grant-in-Aid for Scientific Research on Priority Areas
    • 资助金额:
      $15.36万
    • 财政年份:
      2003
    • 负责人:
      KANEHISA Minoru
    • 依托单位:
    Biological Knowledge Based on Genome Information
    • 批准号:
      08283103
    • 项目类别:
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • 资助金额:
      $555.26万
    • 财政年份:
      1996
    • 负责人:
      KANEHISA Minoru
    • 依托单位:
    Prediction of protein functional sites by multivariate analysis of amino acid sequences
    • 批准号:
      63480514
    • 项目类别:
      Grant-in-Aid for General Scientific Research (B)
    • 资助金额:
      $3.84万
    • 财政年份:
      1988
    • 负责人:
      KANEHISA Minoru
    • 依托单位:
    海外基金