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"Man-Earth System : A scientific approach to realize human society in harmony with the Earth"-Transgenerational Effects of Man-made Environmental Toxic Agents Contaminating the Earth-

"Man-Earth System : A scientific approach to realize human society in harmony with the Earth"-Transgenerational Effects of Man-made Environmental Toxic Agents Contaminating the Earth-
《人地系统:实现人类社会与地球和谐相处的科学途径》-人造环境有毒物质污染地球的跨代效应-
批准号:
05278114
负责人:
NOMURA Taisei
金额:
$73.92万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research on Priority Areas
财政年份:
1993
资助国家:
日本
项目状态:
已结题
起止时间:
1993 至 1997

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中文摘要
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英文摘要
We focus the followings to examine the transgenerational effects of man-made toxic agents contaminating our planet :a) Morphological and functional abnormalities were induced in the offspring of mice, rats, and fish exposed to man-made toxic agents such as dioxin and glyphosate.b) Phthalate gives damage to erythrocytes, and then kills sperm by anoxia. Dioxin may injure the seminal vesicle preceeding the damage to germ cells.c) Repetitive sequence probe Pc-3 was cloned to detect anomalous polymorphism in the offspring of mice exposed to radiation.d) Ecological and genetic studies of radionuclides after Chernobyl catastrophe : Strong biological concentration of radionuclides was observed in mushroom, berries, etc. Genetic effects were detected in human in addition to wild and experimental animals (e.g., frog, Drosophila).
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Fujino,Y., et al.: "Low senstivity of adrenal chromaffin cells to acetylcholine,neostigmine and oxotremorine in 21-day-old rats." Jpn.J.Pharmacol.3. 157-163 (1997)
Fujino,Y., et al.:“21 日龄大鼠的肾上腺嗜铬细胞对乙酰胆碱、新斯的明和氧化震颤素的敏感性较低。”
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藤井,儔子: "Wister今道およびF344/DuCrjラットにおける除草剤グルホシネート・アンモニウムの継世代的影響" 環境科学会誌. 9. 92-94 (1996)
Fujii, Yuko:“除草剂草铵膦对 Wister Imamichi 和 F344/DuCrj 大鼠的跨代影响”环境科学学会杂志 9. 92-94 (1996)。
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99
    Establishment of human benign prostatic hyperplasia model in super-SCID mice and its pathological analysis
    • 批准号:
      26670196
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.41万
    • 财政年份:
      2014
    • 负责人:
      NOMURA Taisei
    • 依托单位:
    Direct effect of radiation and chemicals on human tissues and its mechanism
    • 批准号:
      23241023
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $31.45万
    • 财政年份:
      2011
    • 负责人:
      NOMURA Taisei
    • 依托单位:
    放射線、化学物質の継世代的(遺伝的)影響-マイクロサテライト突然変異誘発と疾病
    Development and analysis of human organ/tissue damage by fission radionuclides
    • 批准号:
      16201013
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $31.53万
    • 财政年份:
      2004
    • 负责人:
      NOMURA Taisei
    • 依托单位:
    海外基金