Simplified teledermoscopy for early detection of melanoma and a screening of nevi.

简化的远程皮肤镜检查用于早期发现黑色素瘤和筛查痣。

• 批准号: 14570822
• 负责人: TANAKA Masaru
• 金额: $ 1.86万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14570822/
• 关键词: dermoscopy; melanoma; melanocytic nevus; tele-diagnosis; pigmented skin lesion; ダーモスコープ; 電子メール; 母斑細胞母斑

Patients, who agreed to enroll in this study, were photographed of their lesions with USB-Microscope M2. The dermoscopic and clinical photos were taken and saved as digital images in a format of JPEG. Patients were basically followed up every three month. All the saved images were sent to Kobayashi and Soyer via e-mails. The number of enrolled patients was twelve in total. The lesions included seborrheic keratosis, solar lentigo as well as melanocytic nevi. Those diagnosis and dermoscopic findings should be carefully evaluated. The dark images and bad white-balanced images were standardized based on surrounding skin color. Statistical analysis was not performed because the tele-diagnosed cases were a few. Correctly diagnosed rate was approximately 90%. It was demonstrated that fewer pixels were enough for correct diagnosis. However, longer follow-up period would be preferred, since only little changes might be observed, if it is a malignant lesion. There was no malignant melanoma case. It was depicted that this study has low possibility of finding melanoma. However, many variety of pigmented skin lesions, including basal cell carcinoma, seborrheic keratosis and solar lentigo, might be involved.

同意入组本研究的患者使用USB显微镜M2拍摄其病变照片。拍摄皮肤镜和临床照片，并以JPEG格式保存为数字图像。患者基本上每三个月随访一次。所有保存的图像都通过电子邮件发送给了小林和索耶。入组患者总数为12例。皮损包括脂溢性角化病、日光性雀斑样痣和黑素细胞痣。这些诊断和皮肤镜检查结果应仔细评估。暗图像和差的白平衡图像基于周围皮肤颜色进行标准化。由于远程诊断病例较少，因此未进行统计分析。正确诊断率约90%。结果表明，较少的像素就足以正确诊断。然而，如果是恶性病变，则最好是较长的随访期，因为可能仅观察到很小的变化。无恶性黑素瘤病例。据描述，本研究发现黑色素瘤的可能性较低。然而，许多色素性皮肤病变，包括基底细胞癌，脂溢性角化病和日光性雀斑样痣，可能涉及。

项目成果

Oka H, Hashimoto M, Iyatomi H, Argenziano G, Soyer HP, Tanaka M: "Internet-based program for automatic discrimination of dermoscopic images between melanomas and Clark nevi."Br J Dermatol. (in press). (2004)

Oka H、Hashimoto M、Iyatomi H、Argenziano G、Soyer HP、Tanaka M：“基于互联网的程序，用于自动区分黑色素瘤和克拉克痣之间的皮肤镜图像。”Br J Dermatol。

Oka H et al.: "Linear discriminant analysis of dermoscopic parameters for differentiation of early melanomas from Clark nevi."Melanoma Research. in press.

Oka H 等人：“用于区分早期黑色素瘤和克拉克痣的皮肤镜参数的线性判别分析。”黑色素瘤研究。

Oka H et al.: "Internet-based program for automatic discrimination of dermoscopic images between melanomas and Clark nevi."Br J Dermatol. in press.

Oka H 等人：“基于互联网的程序，用于自动区分黑色素瘤和克拉克痣之间的皮肤镜图像。”Br J Dermatol。

Argenziano G et al.: "Dermoscopy of pigmented skin lesions : results of a consensus meeting via the Internet."J Am Acad Dermatol. 48. 679-693 (2003)

Argenziano G 等人：“色素性皮肤病变的皮肤镜检查：通过互联网达成共识的结果。”J Am Acad Dermatol。

Piccolo D, Soyer HP, Burgdorf W, Talamini R, Peris K, Bugatti L, Canzonieri V, Cerroni L, Chimenti S, De Rosa G, Filosa G, Hoffmann R, Julis I, Kutzner H, Manente L, Misciali C, Schaeppi H, Tanaka M, Tyler W, Zelger B, Kerl H: "Concordance between telepat

Piccolo D、Soyer HP、Burgdorf W、Talamini R、Peris K、Bugatti L、Canzonieri V、Cerroni L、Chimenti S、De Rosa G、Filosa G、Hoffmann R、Julis I、Kutzner H、Manente L、Misciali C、Schaeppi