NMR-spectrometer (400 MHz) for measurements in the liquid phase

用于液相测量的 NMR 波谱仪 (400 MHz)

• 批准号: 470767093
• 金额: --
• 依托单位: Gottfried Wilhelm Leibniz Universität Hannover
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2021
• 资助国家: 德国
• 起止时间: 2020-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/470767093?language=en
• 关键词: NMR; spectrometer; 400; MHz; measurements

Liquid-phase NMR spectroscopy is a central analytical method in the area of molecular chemistry, which is applied on a daily basis in any chemical institute. It delivers information about the local environment of NMR-active nuclei and, thus, about the structure of compounds. Because of a stronger focus in research at the Leibniz-University Hannover in the field of chemical material science, organic-inorganic materials and polymers, which is documented by numerous, recent appointments for professor positions, there is now a significantly higher need for NMR-measurements in the liquid phase compared to the past. In addition to higher demand, there are also new scientific tasks, which require equipment with a configuration designed for the particular scientific projects. This involves measurements on compounds containing hetero-elements, which are characterized by low abundance or sensitivity, as well as diffusion measurements. The first liquid-phase NMR spectrometer for chemical material science should be situated in a new central laboratory of the university, cfMATCH (core facility multi-scale analysis techniques for the chemical material science). The machine will, thus, be accessible for a large group of users spanning the entire university. The main unit (400 MHz) allows to measure Lamour-frequencies down to particularly low frequencies (12.5 MHz) because of a combination with a high-performance console and different probe heads, and the possibility to use enlarged sample volumes (10mm). Besides standard nuclei (1H, 13C) one can perform the full width band width suitable for nuclei such as 7Li, 11B, 15N, 19F, 27Al, 29Si, 31P, 57Fe, 103Rh, 105Pd, 111Cd, 119Sn, 151Eu, 157Gd, 183W, 195Pt, and 207Pb. Temperature-dependent effects and kinetics can be investigated using the temperature adjustment of the probe heads in the range -100°C till +150°C. Diffusion ordered spectroscopy (DOSY) can be performed in a magnet field gradient in z-direction of up to 50 G/cm. The advantage of such a relatively high field gradient is that it enables the study of compounds with large hydrodynamic radius and, thus, small diffusion rates. The measurement of confined diffusion processes is possible as well.

液相核磁共振光谱是分子化学领域的核心分析方法，在任何化学研究所都是日常应用。它提供有关NMR活性核的局部环境的信息，从而提供有关化合物结构的信息。由于汉诺威莱布尼茨大学在化学材料科学、有机-无机材料和聚合物领域的研究更加集中，最近任命了许多教授职位，与过去相比，现在对液相NMR测量的需求显着增加。除了更高的要求外，还有新的科学任务，需要为特定科学项目设计配置的设备。这涉及对含有杂元素的化合物的测量，其特点是丰度或灵敏度低，以及扩散测量。第一台用于化学材料科学的液相NMR光谱仪应该位于该大学新的中心实验室cfMATCH（化学材料科学的核心设施多尺度分析技术）。因此，整个大学的大量用户都可以使用这台机器。主单元（400 MHz）可以测量低至特别低的频率（12.5 MHz）的拉穆尔频率，因为它结合了高性能控制台和不同的探头，并且可以使用更大的样品体积（10 mm）。除了标准核（1H，13 C），还可以进行适合于核的全宽带宽，例如7 Li，11B，15 N，19 F，27 Al，29 Si，31 P，57 Fe，103 Rh，105 Pd，111 Cd，119 Sn，151 Eu，157 Gd，183 W，195 Pt和207 Pb。通过在-100 ° C至+150 ° C范围内调节探头的温度，可以研究温度相关效应和动力学。扩散有序光谱（DOSY）可以在z方向高达50 G/cm的磁场梯度中进行。这样一个相对较高的场梯度的优点是，它使化合物的研究具有大的流体动力学半径，因此，小的扩散速率。限制扩散过程的测量也是可能的。