Visualising below the tip of the proteome iceberg

蛋白质组冰山一角下方的可视化

• 批准号: LP0561182
• 负责人: Prof Mark Baker
• 金额: $ 17.51万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0561182
• 关键词: Visualising; below; tip; proteome; iceberg

Proteomics attempts to understand human biology by examining the protein components of cells and tissues. Unfortunately, currently available technology only allows approximately 10% of the complexity of these cells and tissues to be concurrently investigated. This project will the physical, chemical and functional properties of protein classes for enrichment, as well as improve technologies for protein visualization, identification and characterization. These approaches will allow the scientific community to further mine beneath the surface of the proteomics 'iceberg'.

蛋白质组学试图通过检测细胞和组织的蛋白质成分来了解人类生物学。不幸的是，目前可用的技术只能同时研究这些细胞和组织的复杂性的大约10%。该项目将研究蛋白质类的物理、化学和功能特性，以进行富集，并改进蛋白质可视化、鉴定和表征的技术。这些方法将使科学界能够进一步挖掘蛋白质组学“冰山”表面之下。