Development of methods for quantitative description and perturbation of biomolecular pathways and networks
Development of methods for quantitative description and perturbation of biomolecular pathways and networks
批准号:
17017004
负责人:
ITO Takashi
金额:
$66.56万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research on Priority Areas
财政年份:
2005
资助国家:
日本
项目状态:
已结题
起止时间:
2005 至 2009
中文摘要
点击翻译按钮获取中文摘要
英文摘要
As a basis for understanding dynamics of biomolecular pathways and networks, we developed novel methods for absolute quantification of gene expression using next generation DNA sequencing, absolute quantification of protein-protein interactions and quantitative analysis of ubiquitinated proteomes by mass spectrometry, and real-time monitoring of intracellular metabolites using FRET.
期刊论文(33)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Absolute quantification of budding yeast transcriptome by means of competitive PCR between genomic and complementary DNAs
通过基因组和互补 DNA 之间的竞争性 PCR 对芽殖酵母转录组进行绝对定量
DOI:
--
发表时间:
2008
期刊:
BMC Genomics 9
影响因子:
--
作者:
[Miura, F., Kawaguchi, N., Yoshida, M., Uematsu, C., Kito, K., Sakaki, Y., Ito, T.]
通讯作者:
T.
A novel, Cdc42-interacting domain of the yeast polarity establishment protein Bem1 : implications for modulation of mating pheromone signaling.
酵母极性建立蛋白 Bem1 的新型 Cdc42 相互作用结构域:对交配信息素信号传导调节的影响。
DOI:
--
发表时间:
2007
期刊:
J. Biol. Chem. 282
影响因子:
--
作者:
[Yamaguchi, Y., Ota, K., Ito, T.]
通讯作者:
T.
DOI:
10.1111/j.1365-2443.2008.01228.x
发表时间:
2008-10-01
期刊:
GENES TO CELLS
影响因子:
2.1
作者:
[Ota, Kazuhisa, Kito, Keiji, Ito, Takashi]
通讯作者:
Ito, Takashi
DOI:
10.1126/stke.4012007re6
发表时间:
2007-08
期刊:
Science's STKE
影响因子:
--
作者:
[H. Sumimoto;S. Kamakura;Takashi Ito]
通讯作者:
H. Sumimoto;S. Kamakura;Takashi Ito
DOI:
10.1002/pro.266
发表时间:
2009-12
期刊:
Protein Science
影响因子:
8
作者:
[S. Okada;K. Ota;Takashi Ito]
通讯作者:
S. Okada;K. Ota;Takashi Ito
共 22 条
A novel therapeutic strategy targeting HMGB1 isoforms in sepsis
-
批准号:18H02904
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.15万
-
财政年份:2018
-
负责人:ITO Takashi
-
依托单位:
A Comprehensive Analysis of Direct Democracy in the Case of Local Government and Referendums in Osaka through Repeated Cross-sectional Surveys
-
批准号:17K13844
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.91万
-
财政年份:2017
-
负责人:ITO Takashi
-
依托单位:
Chromatin remodeling and Induction of pluripotency via Sox2/TBP complex
-
批准号:17H04044
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.4万
-
财政年份:2017
-
负责人:ITO Takashi
-
依托单位:
Helicobacter pylori induces somatic mutations in TP53 via overexpression of CHAC1 in infected gastric epithelial cells
-
批准号:16K19077
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.5万
-
财政年份:2016
-
负责人:ITO Takashi
-
依托单位:
A history of animal welfare in modern Britain
-
批准号:16K03108
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2016
-
负责人:ITO Takashi
-
依托单位:
Therapeutic strategy targeting extracellular histones in sepsis-associated DIC
-
批准号:15H05684
-
项目类别:Grant-in-Aid for Young Scientists (A)
-
资助金额:$15.31万
-
财政年份:2015
-
负责人:ITO Takashi
-
依托单位:
Extracellular histones stimulate endothelial cells to release unusually-large von Willebrand factor multimer: mechanistic insight into the pathogenesis of lethal coagulopathy
-
批准号:26670789
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2014
-
负责人:ITO Takashi
-
依托单位:
Extracellular histones as a myocardial depressant factor
-
批准号:25670763
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2013
-
负责人:ITO Takashi
-
依托单位:
Transomic analysis of adaptation induced by a synthetic gene circuit
-
批准号:25640110
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.58万
-
财政年份:2013
-
负责人:ITO Takashi
-
依托单位:
HMGB1-induced vaspressin deficiency contributes to septic shock
-
批准号:24390402
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.73万
-
财政年份:2012
-
负责人:ITO Takashi
-
依托单位:
A role of extracellular histones as mediators of death in sepsis
-
批准号:24659797
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2012
-
负责人:ITO Takashi
-
依托单位:
Improvement of the flypast method for pulsed muSR measurements on a small amount of sample
-
批准号:24710101
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.5万
-
财政年份:2012
-
负责人:ITO Takashi
-
依托单位:
Fecal microflora composition change in neonates with intensive theraphy
-
批准号:24791120
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.66万
-
财政年份:2012
-
负责人:ITO Takashi
-
依托单位:
Role of CDC42 in pro-inflammatory phenotype of senescent vascular endothelial cells
-
批准号:24790272
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.83万
-
财政年份:2012
-
负责人:ITO Takashi
-
依托单位:
Genome-wide in vivo footprinting by next-generation sequencing
-
批准号:24651226
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.58万
-
财政年份:2012
-
负责人:ITO Takashi
-
依托单位:
Development of Oral Infection Control System with Natural and Artificial materials
-
批准号:24890134
-
项目类别:Grant-in-Aid for Research Activity Start-up
-
资助金额:$1.91万
-
财政年份:2012
-
负责人:ITO Takashi
-
依托单位:
A Study on the Making of Inventory of the Various Disaster Revival Projects and their Transformation Processes Based on the Chronological Order
-
批准号:24560649
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.49万
-
财政年份:2012
-
负责人:ITO Takashi
-
依托单位:
Genome-wide analysis of chromatin structure at single molecule resolution by base modification and next-generation sequencing
-
批准号:23651199
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.58万
-
财政年份:2011
-
负责人:ITO Takashi
-
依托单位:
Politics of animal ethics in modern Britain
-
批准号:23820061
-
项目类别:Grant-in-Aid for Research Activity Start-up
-
资助金额:$2.0万
-
财政年份:2011
-
负责人:ITO Takashi
-
依托单位:
DAMPs : novel molecular targets for DIC therapy
-
批准号:23890166
-
项目类别:Grant-in-Aid for Research Activity Start-up
-
资助金额:$1.08万
-
财政年份:2011
-
负责人:ITO Takashi
-
依托单位:
海外基金