CONNECTION SELECTIVITY IN CEREBRAL CIRCUITRY

阐明新皮质的组织原理对于理解大脑皮层的功能至关重要。我们定量鉴定了兴奋性锥体细胞亚型和GABA能非锥体细胞亚型。我们发现神经元亚型表现出选择性连接，GABA能细胞在局部和全局节律中放电。因此，新皮质的局部突触组织和放电活动是根据全球区域间回路及其振荡相互作用来确定的。

Elucidation of neocortical organization principles is crucial for understanding the function of the cerebral cortex. We quantitatively identified excitatory pyramidal and GABAergic nonpyramidal cell subtypes. We found that the neuron subtypes exhibited selective connectivity and that GABAergic cells discharged during the local and global rhythms. Thus, the local synaptic organization and firing activity in the neocortex are specified according to global inter-regional circuits and their oscillatory interaction.