Integration of cortical micro and macro circuits

动物利用新皮层，特别是额叶皮层和基底神经节，根据过去的动作及其结果选择最合适的动作。为了理解这个大脑过程，我们应该知道额叶皮层的神经元组成和它们之间的突触相互作用。本研究阐明了投射到基底节区和其他皮层下结构的输出细胞的功能组织和突触连接规律。这些发现表明，新皮层局部回路由根据不同的皮层外投射组织的连接子网络组成。

Using neocortex, especially frontal cortex, and basal ganglia, animals select the most appropriate actions according the past action and its result. To understand this brain process, we should know the neuron composition of the frontal cortex and their synaptic interactions. This research has clarified the functional organization and synaptic connection rules of output cells projecting to the basal ganglia and other subcortical structures. These findings indicate that the neocortical local circuit consists of connection subnetworks organized according to diverse extracortical projections.