课题基金 / 基金详情

A study on the suppression protocol on proliferation of solid tumors regulating cancer stem cells and neo-vascularization

A study on the suppression protocol on proliferation of solid tumors regulating cancer stem cells and neo-vascularization
实体瘤增殖抑制方案调节癌症干细胞和新生血管的研究
批准号:
20248032
负责人:
MATSUDA Hiroshi
金额:
$28.29万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

项目摘要

项目成果

MATSUDA Hiroshi的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
In a malignant solid carcinoma, proliferation of cancer cells are sometimes accelerated after a surgery and radiation therapy and a cancer may recur in a short term. It is thought that a cancer stem cell of the drug resistance and the high vascularization inducibility bring the rapid expansion of the cancer tissue, but the control method is not yet found. Based on the author's past research on mast cell tumors, we evaluated a silencing therapy or a gene control therapy for the endogenous inhibitors for vascularization and hypoxia inducible factors which controlled neo-vascularization. We developed effective therapy for controlling neo-vascularization. In addition, we elucidated mechanism of the drug resistance of cancer stem cells and obtained fundamental researche data for establishment of a novel therapy.
期刊论文(39)
专著(0)
科研奖励(0)
会议论文
ヒト中皮腫細胞における腫瘍性増殖制御分子としての転写因子NF-κBの役割
转录因子 NF-κB 作为人间皮瘤细胞肿瘤生长控制分子的作用
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Nishikawa S, Tanaka A, Ohm・ri K, MatsudaH]
通讯作者: MatsudaH
Inhibition of nuclear factor-KQ activity restored glucocarticoid sensitivity in lymphocytes and mast cells.
抑制核因子-KQ 活性可恢复淋巴细胞和肥大细胞中的糖皮质激素敏感性。
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Matsuda A, Tanaka A, Ohmori K, Matsuda H.]
通讯作者: Matsuda H.
DOI: 10.1016/j.rvsc.2010.03.017
发表时间: 2010-12-01
期刊: RESEARCH IN VETERINARY SCIENCE
影响因子: 2.4
作者: [Matsuda, A., Tanaka, A., Matsuda, H.]
通讯作者: Matsuda, H.
DOI: 10.1111/j.1365-3164.2010.00900.x
发表时间: 2010
期刊: Vet Dermatol
影响因子: 1.4
作者: [Ohmori K, Tanaka A, Makita Y, Takai M, Yoshinari, Y, Matsuda H.]
通讯作者: Matsuda H.
30
    Evaluation index of ride comfort and fatigue for drivers and occupants by vehicle vibration
    • 批准号:
      19K04739
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.5万
    • 财政年份:
      2019
    • 负责人:
      MATSUDA Hiroshi
    • 依托单位:
    Development of an efficient and low cost diagnostic method for soundness of bridges by optical measurement method without temporary scaffolding
    • 批准号:
      17H03298
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.15万
    • 财政年份:
      2017
    • 负责人:
      MATSUDA Hiroshi
    • 依托单位:
    Redefinition of intractable inflammatory diseases based on mast cell activation syndrome
    Effect of sound on vibration sensation for horizontal vibration generated in vehicle and amusement facility
    • 批准号:
      16K06622
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.08万
    • 财政年份:
      2016
    • 负责人:
      MATSUDA Hiroshi
    • 依托单位:
    国内基金
    海外基金
    瘤内链球菌促进STAT3的O-GlcNAc修饰驱动鼻咽癌免疫抑制微环境的机制研究
    • 批准号:
      JCZRLH202600778
    • 项目类别:
      省市级项目
    • 资助金额:
      --
    • 批准年份:
      2026
    • 负责人:
    • 依托单位:
    SDC1通过MMP11+CAF的细胞外基质重塑促进子宫颈癌化学免疫联合治疗耐药的机制研究
    • 批准号:
      JCZRQNB202600504
    • 项目类别:
      省市级项目
    • 资助金额:
      --
    • 批准年份:
      2026
    • 负责人:
    • 依托单位:
    多模态精准导航引导肝内胆管癌淋巴结清扫的动态示踪与机制探索
    抗BNLF2b抗体联合circRNA构建鼻咽癌早期诊断模型及机制研究