Enzymatic synthesis of useful chemicals from nitrogen-containg substrates

在这项研究中，我们对许多作用于含氮化合物的植物和微生物酶进行了表征，发现了它们的“醛-腈途径”，并将它们用于合成各种有用的化学物质。它们催化的大部分反应不能在合成化学反应中进行。我们利用了以下几种酶，如腈水合酶、D-和L立体专一性氨基酸酰胺酶、α-氨基-e-氨基丙内酰胺外消旋酶、植物羟基腈裂解酶等，来生产有用的含氮化合物。

In this research, we characterized many plant and microbial enzymes acting on nitrogen containing compounds, found in their "Aldoxime-Nitrile Pathways", and utilized them in the synthesis of various useful chemicals. Most of the reactions they catalyze cannot be done in the synthetic chemical reactions. We utilized the following enzymes, such as nitrile hydratases, D- and L-stereospecific amino acid amidases, a-amino-e-aminocaprolactam racemase, plant hydroxynitrile lyases, etc., in the production of useful nitrogen containing compounds.