Mechanisms of disease development in pine wilt disease based on the interaction of biomolecules

基于生物分子相互作用的松材线虫病发病机制

• 批准号: 23248024
• 负责人: SAHASHI NORIO
• 金额: $ 31.87万
• 依托单位: Forestry and Forest Products Research Institute
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (A)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-23248024/
• 关键词: マツ材線虫病; マツノザイセンチュウ; 発病機構; 生体分子; 感染症; 宿主－寄生者相互作用; 網羅的解析; マツ林線虫病; 宿主-寄生者相互作用

To understand the pathogenicity (or virulence) of Bursaphelencus xylophilus (a causal pathogen of pine wilt disease) and the mechanisms of resistance (or susceptibility) of pine trees, physiological, histoathological and molecular biological studies were carried out. High quality draft genome sequence of Bursaphelenchus xylophilus was completed. Furthermore, many important factors associated with disease development were identified in both nematode and pine tree. The results presented here will contribute for further understanding the mechanisms of pine wilt disease development.

为了解松材线虫（Bursaphelencus xylophilus）的致病性（或毒力）和松树的抗病（或感病）机制，本研究从生理、组织病理和分子生物学等方面进行了研究。完成了松材线虫高质量的基因组序列草图。此外，许多重要的因素与疾病的发展，确定在线虫和松树。本研究结果将有助于进一步了解松材线虫病的发病机理。

项目成果

Pinewood nematode-associated bacteria contribute to oxidative stress rstance of Bursaphelenchus xylophilus

松材线虫相关细菌有助于松材线虫的氧化应激抵抗

• 发表时间: 2013
• 期刊: BMC Mcrobiology
• 作者: Vicente;C.S.L.;Ikuyo;Y.;Mota;M.;Hsegawa;K.
• 通讯作者: K.

Bursaphelenchus niphades n. sp (Tylenchina: Aphelenchoididae) amensally associated with Niphades variegatus (Roelofs) (Coleoptera: Curculionidae)

• DOI: 10.1163/15685411-00002763
• 发表时间: 2014-01-01
• 期刊: NEMATOLOGY
• 影响因子: 1.2
• 作者: Tanaka, Suguru E.;Tanaka, Ryusei;Kanzaki, Natsumi
• 通讯作者: Kanzaki, Natsumi

房総半島におけるヒメコマツ実生苗のマツ材線虫病抵抗性について

关于房总半岛日本松苗的松材线虫病抗性

• 发表时间: 2013
• 作者: Kawachi;M.;Nagasaki-Takeuchi;N.;Kato;M.;Maeshima;M.;Ishiyama N;軽込 勉
• 通讯作者: 軽込 勉

マツノザイセンチュウ研究の新たな展開

松树线虫研究新进展

• 发表时间: 2011
• 作者: Kazuyoshi Futai;Ryoji Shinya;Yuko Takeuchi;Mitsuyoshi Ueda;新屋良治
• 通讯作者: 新屋良治

The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery.

• DOI: 10.1186/gb-2013-14-8-r88
• 发表时间: 2013-08-28
• 期刊: Genome biology
• 影响因子: 12.3
• 作者: Laing R;Kikuchi T;Martinelli A;Tsai IJ;Beech RN;Redman E;Holroyd N;Bartley DJ;Beasley H;Britton C;Curran D;Devaney E;Gilabert A;Hunt M;Jackson F;Johnston SL;Kryukov I;Li K;Morrison AA;Reid AJ;Sargison N;Saunders GI;Wasmuth JD;Wolstenholme A;Berriman M;Gilleard JS;Cotton JA
• 通讯作者: Cotton JA