Mechanisms of disease development in pine wilt disease based on the interaction of biomolecules

为了解松材线虫病病原菌松材线虫的致病力(或致病力)和松树对松材线虫的抗性(或感病)机制，对松材线虫的生理、组织病理学和分子生物学进行了研究。完成了松材线虫高质量的基因组草图测序。此外，在线虫和松树中都发现了许多与疾病发展相关的重要因素。本文的研究结果将有助于进一步了解松材线虫病的发病机理。

To understand the pathogenicity (or virulence) of Bursaphelencus xylophilus (a causal pathogen of pine wilt disease) and the mechanisms of resistance (or susceptibility) of pine trees, physiological, histoathological and molecular biological studies were carried out. High quality draft genome sequence of Bursaphelenchus xylophilus was completed. Furthermore, many important factors associated with disease development were identified in both nematode and pine tree. The results presented here will contribute for further understanding the mechanisms of pine wilt disease development.