STUDIES ON ETHNOPHARMACOGNOSY AND UNUSED MEDICINAL RESOURCES IN AFRICA.

目前的研究包括对马赛人、基库尤人、坎巴人、罗人、迪戈人和吉里马人的民族药物进行调查，以期建立选择和使用这些药物的基础。在收集到的90种民族药中，有60种进行了植物鉴定，并进行了对c-AMP磷酸二酯酶（PDE）和心脏活性的抑制作用筛选。在被试药物中，Masai金合欢属6种、Anonaceae属8种对c-AMP PDE有抑制作用。和心脏活动。另一方面，通过对非洲未利用的药用资源的研究，我们实验室从肯尼亚的根菌科（Rhizophoraceae）的4种cassiourrea spp. .中获得了几种新的含硫生物碱化合物，即我们命名的异异assipourine， guinine - d和euryoidine。

The current research involved a survey of the ethno-medicines of Masai, Kikuyu, Kanba, Luo, Digo, and Giriama with a viwe of establishing the base of selection and use of the remedies. Of 90 ethnomedicines collected, 60 species have been identified botanically, and subjected to screening for inhibitory effects on c-AMP phosphodiesterase (PDE) and cardial activity. Among the medicines tested, 6 species including Acacia genus of Masai and 8 species including Anonaceae genus exhibited inhibitory effects on c-AMP PDE., and cardial activity respectively.On the other hand, study on unused medicinal resources in Africa has brought in our laboratory several new sulfur containig alkaloid compounds from 4 species of Cassipourea spp. (Rhizophoraceae) in Keny, viz. isocassipourine, guinesine-D and euryoidine named by us.