Small Molecule NMR Facility for Accelerated Drug Discovery
Small Molecule NMR Facility for Accelerated Drug Discovery
批准号:
LE0453651
负责人:
Prof Frances Separovic
金额:
$60.51万
依托单位国家:
澳大利亚
项目类别:
Linkage Infrastructure, Equipment and Facilities
财政年份:
2003
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2003-12-11 至 2006-12-31
中文摘要
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英文摘要
This project will accelerate the drug discovery process by establishing a world-class small-molecule Nuclear Magnetic Resonance (NMR) facility. The requested instrumentation will enable high throughput structural analysis of synthetic lead compounds, expedite natural product isolation and identification and enhance NMR-based drug screening. This facility will support both existing and new programs in Victorian universities, particularly Medicinal and Biological Chemistry, and achieve internationally competitive research capabilities. Outcomes will include the development of new pharmaceuticals, increased local and international collaboration and the training of new scientists in state-of-the-art spectroscopic techniques for identification of natural products and synthetic molecules of pharmacological importance.
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会议论文
Mechanism of Bacterial Resistance to Antimicrobial Peptides
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批准号:nhmrc : 1142750
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项目类别:Project Grants
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资助金额:$45.68万
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财政年份:2018
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负责人:Prof Frances Separovic
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依托单位:
Mechanism of Bacterial Resistance to Antimicrobial Peptides
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批准号:nhmrc : GNT1142750
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项目类别:Project Grants
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资助金额:$67.56万
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财政年份:2018
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负责人:Prof Frances Separovic
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依托单位:
Atomic details of antimicrobial peptides at work in live cells
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批准号:DP160100959
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项目类别:Discovery Projects
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资助金额:$26.47万
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财政年份:2016
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负责人:Prof Frances Separovic
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依托单位:
Dynamic Nuclear Polarisation system for molecular structure determination
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批准号:LE160100120
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$53.34万
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财政年份:2016
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负责人:Prof Frances Separovic
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依托单位:
Biomembrane Interactions Facility
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批准号:LE140100068
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$18.67万
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财政年份:2014
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负责人:Prof Frances Separovic
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依托单位:
Structure and activity determination of membrane-active peptides
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批准号:DP140102127
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项目类别:Discovery Projects
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资助金额:$23.07万
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财政年份:2014
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负责人:Prof Frances Separovic
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依托单位:
Advanced characterisation of materials by nuclear magnetic resonance
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批准号:LE110100097
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$40.01万
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财政年份:2011
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负责人:Prof Frances Separovic
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依托单位:
Membrane-associated structure and the effect of metals on Abeta peptide from Alzheimer's disease
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批准号:DP0984815
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项目类别:Discovery Projects
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资助金额:$24.89万
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财政年份:2009
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负责人:Prof Frances Separovic
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依托单位:
Membrane Protein Structure and Interaction Facility
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批准号:LE0668017
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$69.81万
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财政年份:2006
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负责人:Prof Frances Separovic
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依托单位:
Membrane interactions and neurotoxicity of Amyloid Abeta peptides from Alzheimer's disease.
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批准号:DP0664601
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项目类别:Discovery Projects
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资助金额:$22.86万
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财政年份:2006
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负责人:Prof Frances Separovic
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依托单位:
Membrane structure and lipid interactions of the pore-forming toxin Equinatoxin II by NMR.
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批准号:DP0343833
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项目类别:Discovery Projects
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资助金额:$19.9万
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财政年份:2003
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负责人:Prof Frances Separovic
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依托单位:
国内基金
海外基金
D-A类共轭聚合物晶界内部tie molecule构象调控
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批准号:51573185
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项目类别:面上项目
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资助金额:70.0万元
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批准年份:2015
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负责人:韩艳春
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依托单位:
耦合可积系统及其molecule解的研究
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批准号:11026119
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项目类别:数学天元基金项目
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资助金额:3.0万元
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批准年份:2010
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负责人:王红艳
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依托单位: