Biomembrane Interactions Facility

生物膜相互作用设施

• 批准号: LE140100068
• 负责人: Prof Frances Separovic
• 金额: $ 18.67万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2015-09-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE140100068
• 关键词: Biomembrane; Interactions; Facility

Biomembrane interactions facility: Characterisation of membrane interactions is important for further advances in biomedical science and drug design. The biomembrane interactions facility will provide modern infrastructure to study membrane biophysics and membrane protein structure and interactions in mammalian, protozoan and bacterial cells. The facility will include a solid-state nuclear magnetic resonance spectrometer and optical analytical instrumentation and biosensor equipment. These will enable determination of molecular structure and dynamics within biomembranes and determination of the rates and mechanisms of cell membrane processes; nanoscale measurement of cell membrane properties; and resolution of the interactions between membrane components in cells.

生物膜相互作用设施：膜相互作用的表征对生物医学科学和药物设计的进一步发展至关重要。生物膜相互作用设施将为研究哺乳动物、原生动物和细菌细胞中的膜生物物理、膜蛋白结构和相互作用提供现代化的基础设施。该设施将包括固态核磁共振光谱仪、光学分析仪器和生物传感器设备。这些将能够确定生物膜内的分子结构和动力学，并确定细胞膜过程的速率和机制；细胞膜性质的纳米尺度测量；以及细胞中膜组分之间相互作用的解析。