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Studies on the effects of minor dental surgery on oxygen consunption and myocardial function.

小型牙科手术对耗氧量和心肌功能影响的研究。

基本信息

批准号：
60570914
负责人：
FUKUSHIMA Kazuaki
金额：
$ 0.9万
依托单位：
Hokkaido University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1985
资助国家：
日本
起止时间：
1985 至 1987
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-60570914/
关键词：
Dental Surgery Oxygen Consumption 心機能

项目摘要

we investigated the effects of dental local anesthesia and minor dental surgery on oxygen consunption(Vo2),carbon dioxide production(Vco2),minute volume(Ve),tidal volume(Vt),respiratory rate (RR) and myocardial function(STI).We found that:1) Epinephrine used concomitantly with lidocaine for dental local anesthesia caused an increase in Vo2,Vco2,Ve, and had positive inotropic effect. However, these changes were slight on healthy adults. Therefore, it was concluded that intraoral injections of lidocaine and epinephrine for dental procedures had minimal clinical effects on oxygen consumption and myocardial function.2) Minor dental surgery on healthy adults caused an increase in Vo2, Vco2, Ve and had positive inotropic effect. However, these changes were slight and were minimized by intravenous sedation by diazepam. Therefor, we believe that these changes were mainly due to the psychological stress of the dental treatment.3) In the patients with hypertension, it was observed that Vo2, Vco2, Ve and myocardial function tended to increase but with no significant changes under the surgical procedures with intravenous sedation. The results was similar to that in healthy adults. Therefor, one implication from the viepoint of oxygen consumption or myocardial function is that sedation technique should be used for minor dental surgery in the patients with hypertension.

本文观察了牙科局部麻醉和牙科小手术对氧耗量（Vo_2）、二氧化碳产生量（Vco_2）、每分钟通气量（Ve）、潮气量（Vt）、呼吸频率（RR）和心肌功能（STI）的影响，结果发现：1）牙科局部麻醉时，肾上腺素与利多卡因合用，可使Vo_2、Vco_2、Ve增加，并有正性肌力作用。然而，这些变化在健康成年人身上很轻微。因此，可以得出结论，口腔内注射利多卡因和肾上腺素的牙科手术对耗氧量和心肌功能的临床影响最小。2）对健康成人的小牙科手术引起Vo2，Vco2，Ve增加，并具有正性肌力作用。然而，这些变化是轻微的，并通过地西泮静脉镇静最小化。3）高血压患者在静脉镇静手术治疗下，Vo2、Vco2、Ve及心肌功能有增加的趋势，但无明显变化。结果与健康成人相似。因此，从耗氧量或心肌功能的角度考虑，高血压患者的牙科小手术应采用镇静技术。