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Effects of hormones on enzynoes in rat nephron segment.-For the protection of isclemmic acute renal failure-

Effects of hormones on enzynoes in rat nephron segment.-For the protection of isclemmic acute renal failure-
激素对大鼠肾单位段酶的影响-对缺血性急性肾功能衰竭的保护-
批准号:
61570306
负责人:
TOMITA Kimio
金额:
$1.34万
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1986
资助国家:
日本
项目状态:
已结题
起止时间:
1986 至 1987

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中文摘要
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英文摘要
Effects of vasopressin, aldosteronl on enzymes were investigated in rat nepbron segments.Vasopressin stimulated Na-K-ATPase activity in rat cortical collecting duct. The stimulative effects were detected following the treat ment about 3 days. Simian stimulation occured 7th day treat ment's.Kininase may be one of the rate limiting factor in the kallikrein-kimin system. Kininase was also invert・gcted along the nepluon. Kinimase was detected in medullary Collecting duct. The acticity acereased following the trecut ment of aldosterone. for 3.7 days.These hormcrce may have protective effect eithen by stimulating Na-K-ATPase or by decreasing kininase.
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作者: []
通讯作者:
Kimio Tomita;Akira Owada;Yasuhiko Iino;Naoki Yoshiyama;Tatsuo Shiigai: American Journal of Physiology. 253. F874-F879 (1987)
Kimio Tomita;Akira Owada;Yasuhiko Iino;Naoki Yoshiyama;Tatsuo Shiigai:美国生理学杂志。
DOI: --
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通讯作者:
Kimio Tomita, Akira Owada, Yasuhiko Iino, Naoki Yoshiyama, Tatsuo Shugai.: "Effect of vasopressin on Na-K-ATPase activity in rat cortical collecting duct." American. Journal of physiology. 253. F874-F879 (1987)
Kimio Tomita、Akira Owada、Yasuhiko Iino、Naoki Yoshiyama、Tatsuo Shugai.:“加压素对大鼠皮质集合管 Na-K-ATP 酶活性的影响。”
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Mechanism of prostasin-induced aldosterone production
  • 批准号:
    20390238
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.81万
  • 财政年份:
    2008
  • 负责人:
    TOMITA Kimio
  • 依托单位:
Development of drug by use of protease cascade of prostasin
  • 批准号:
    18390252
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.51万
  • 财政年份:
    2006
  • 负责人:
    TOMITA Kimio
  • 依托单位:
Antibody treatment against hypertension
  • 批准号:
    16390246
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $8.77万
  • 财政年份:
    2004
  • 负责人:
    TOMITA Kimio
  • 依托单位:
Analysis of the function of prostasin in the transgenic mice.
  • 批准号:
    14370321
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $8.83万
  • 财政年份:
    2002
  • 负责人:
    TOMITA Kimio
  • 依托单位:
海外基金