Effects of hormones on enzynoes in rat nephron segment.-For the protection of isclemmic acute renal failure-
Effects of hormones on enzynoes in rat nephron segment.-For the protection of isclemmic acute renal failure-
批准号:
61570306
负责人:
TOMITA Kimio
金额:
$1.34万
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1986
资助国家:
日本
项目状态:
已结题
起止时间:
1986 至 1987
中文摘要
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英文摘要
Effects of vasopressin, aldosteronl on enzymes were investigated in rat nepbron segments.Vasopressin stimulated Na-K-ATPase activity in rat cortical collecting duct. The stimulative effects were detected following the treat ment about 3 days. Simian stimulation occured 7th day treat ment's.Kininase may be one of the rate limiting factor in the kallikrein-kimin system. Kininase was also invert・gcted along the nepluon. Kinimase was detected in medullary Collecting duct. The acticity acereased following the trecut ment of aldosterone. for 3.7 days.These hormcrce may have protective effect eithen by stimulating Na-K-ATPase or by decreasing kininase.
期刊论文(3)
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会议论文
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通讯作者:
Kimio Tomita;Akira Owada;Yasuhiko Iino;Naoki Yoshiyama;Tatsuo Shiigai: American Journal of Physiology. 253. F874-F879 (1987)
Kimio Tomita;Akira Owada;Yasuhiko Iino;Naoki Yoshiyama;Tatsuo Shiigai:美国生理学杂志。
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通讯作者:
Kimio Tomita, Akira Owada, Yasuhiko Iino, Naoki Yoshiyama, Tatsuo Shugai.: "Effect of vasopressin on Na-K-ATPase activity in rat cortical collecting duct." American. Journal of physiology. 253. F874-F879 (1987)
Kimio Tomita、Akira Owada、Yasuhiko Iino、Naoki Yoshiyama、Tatsuo Shugai.:“加压素对大鼠皮质集合管 Na-K-ATP 酶活性的影响。”
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通讯作者:
Mechanism of prostasin-induced aldosterone production
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批准号:20390238
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.81万
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财政年份:2008
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负责人:TOMITA Kimio
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依托单位:
Development of drug by use of protease cascade of prostasin
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批准号:18390252
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.51万
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财政年份:2006
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负责人:TOMITA Kimio
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依托单位:
Antibody treatment against hypertension
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批准号:16390246
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.77万
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财政年份:2004
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负责人:TOMITA Kimio
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依托单位:
Analysis of the function of prostasin in the transgenic mice.
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批准号:14370321
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.83万
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财政年份:2002
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负责人:TOMITA Kimio
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依托单位:
Role of renal arginase in acute renal failure
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批准号:11470219
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$9.34万
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财政年份:1999
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负责人:TOMITA Kimio
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依托单位:
Prevention of acute renal failure by anti-endothelin converting enzyme.
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批准号:09470238
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.26万
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财政年份:1997
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负责人:TOMITA Kimio
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依托单位:
Role of endothelin converting enzyme in essential hypertension
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批准号:09557091
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$3.07万
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财政年份:1997
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负责人:TOMITA Kimio
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依托单位:
Molecular biological analysis of the mechanism of acute renal failure
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批准号:07457242
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.03万
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财政年份:1995
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负责人:TOMITA Kimio
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依托单位:
Elucidation of the mechanism of essential hypertension making a transgenic mice made by putative kallikrein binding protein
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批准号:05557054
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$6.08万
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财政年份:1993
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负责人:TOMITA Kimio
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依托单位:
Elucidation of mechanism of acute renal failure by use molecular biological techniques
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批准号:04454234
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.29万
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财政年份:1992
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负责人:TOMITA Kimio
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依托单位:
Research of the mechanism and treatment for acute renal failure-role of endothelin-
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批准号:02670273
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.47万
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财政年份:1990
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负责人:TOMITA Kimio
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依托单位:
The mechanism and treatment of ischemic acute renal failure -rde of superoxide -
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批准号:63570285
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.47万
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财政年份:1988
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负责人:TOMITA Kimio
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依托单位:
海外基金