Development of Automatic Control System of Artificial Respiration Based on Nonlinear Adaptive Control Method

基于非线性自适应控制方法的人工呼吸自动控制系统的研制

• 批准号: 61570369
• 负责人: WAKAMATSU Hidetoshi
• 金额: $ 1.47万
• 依托单位: University of Fukui (1988)Ashikaga Institute of Technology (1986-1987)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1986
• 资助国家: 日本
• 起止时间: 1986 至 1988
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-61570369/
• 关键词: Artificial respiration; Adaptive control system; 非線形自己回帰移動平均モデル

An automatic control system of artificial respiration is developed to maintain a carbon dioxide concentration within a desired range of value against the effect of irregular metabolic rate change for the help of autonomous respiration or under the use of muscle relaxant and/or open chest surgery. Conventional design methods of control systems cannot be directly applied to an urgent medical care without time consuming and laborious estimation of physiological parameters of patients. A respiratory system is assumed to be represented by a nonlinear autoregressive moving average model with its finite nonlinear order and memory length to which a dead time is introduced, as it is inevitable for the control of such a biological subsystem using gas flow. Thereby, a nonlinear model reference adaptive control technique is applied to the design of the control system with a development of a new type of respirator based on the reduction of necessary physiological knowledge about a patient even for … More an urgent care in the absence of a medical doctor.For a completely automatic design process and an effective application of the control system to clinics in accordance with an individual difference and a physiological state of a patient, a respirator and a necessary information processing system is unified into a unit system, combining software systems of control algorithm and electromechanical apparatus. The ventilation amount of a respirator is controlled by the stroke and frequency of its piston movement which can be actuated by the signals of diaphragm movement of a patient of directly by the signals from a microcomputer. Therefore, an artificial rerspiratory control system can be much dependent not on the rhythm given by computer but on the one characterized by the state of a patient. Heraby, a patient wears a special mask for a ventilation equipped with O_2- and CO_2-sensors for the possible less delay sensing of their concentrations. The safety and reliability of the outomatic control system of artificial respiration are clinically examined in detail. Less

人工呼吸的自动控制系统被开发来将二氧化碳浓度维持在期望的值范围内，以抵抗不规则代谢率变化的影响，以帮助自主呼吸或在使用肌肉松弛剂和/或开胸手术的情况下。如果不费时费力地估计患者的生理参数，传统的控制系统设计方法就无法直接应用于紧急医疗护理。假设呼吸系统由非线性自回归移动平均模型表示，其具有有限的非线性阶数和存储器长度，并引入死区时间，因为使用气流控制此类生物子系统是不可避免的。因此，将非线性模型参考自适应控制技术应用于控制系统的设计，开发了一种新型呼吸器，其基础是减少患者必要的生理知识，即使是在没有医生的情况下进行紧急护理。为了实现完全自动化的设计过程，并根据患者的个体差异和生理状态将控制系统有效地应用于临床，将呼吸器和必要的信息处理系统统一为一个单元 系统，结合控制算法和机电装置的软件系统。呼吸器的通气量由其活塞运动的冲程和频率控制，活塞运动可以由患者的隔膜运动信号或直接由来自微计算机的信号驱动。因此，人工呼吸控制系统在很大程度上不依赖于计算机给出的节律，而是依赖于以患者状态为特征的节律。在此，患者佩戴配备 O_2 和 CO_2 传感器的特殊通气面罩，以尽可能减少对它们浓度的延迟感测。对人工呼吸自动化控制系统的安全性和可靠性进行了详细的临床检验。较少的

项目成果

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S.Kaguei: Chem.Eng.SCi.44. 483-491 (1989)

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Wakamatsu, H.：“通过模型参考自适应控制设计呼吸控制系统”，Instrum & Control Eng.22 (1986)。

H.Wakamatsu: Proc.3rd Multinat.Instrum.Conf.3. 71-75 (1988)

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Wakamatsu, H.: "Application of model reference adaptive control method to control of respiration" Proc. 3rd Multinat. Instrum. Conf.3. 71-75 (1988)

Wakamatsu, H.：“模型参考自适应控制方法在呼吸控制中的应用”Proc。