GaAlAs Laser Therapy in Dentin Hypersensitivity and Histopathological Changes of the Dental Pulp Tissues

GaAlAs激光治疗牙本质过敏和牙髓组织的组织病理学变化

• 批准号: 61570906
• 负责人: SHIMOKOBE Hirokata
• 金额: $ 1.22万
• 依托单位: Hokkaido Univ.
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1986
• 资助国家: 日本
• 起止时间: 1986 至 1987
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-61570906/
• 关键词: Diode Laser; Dentin Hypersensitivity; 歯髄変化; レーザー; 知覚過敏; 象牙質; 半導体

Recent studies have shown the effects of diode laser irradiation in treatment for dentin hypersensitivities. However,the system of the effects still remains unsolved. The conditions and indications of irradiation in the diseases are, therefore, not defined in detail, which decreases clinical reliability of the laser therapy for pain.The study was designed to examine histopathological change of dental pulp tissue by laser irradiation to know the mechanism of the effects.Continuous irradiation at 30mW was performed for 60 and 90 seconds under direct contact of a probe to occlusal surface of the first molars of male Wistar rats by using Ga-Al-As diode laser(<lambda>: 830nm, Osada Electric Co.). The rats were sacrificed 2 weeks after irradiation and the pulp tissues were routinely examined histopathologically under light microscope. Clinical examination also done on the patients having hypersensitive dentinunder their consents.Experiments indicate ; 1) No differences were detected in histopathological appearance of pulp tissues between irradiated and non-irradiated groups in this study. Since loss of pain by laser irradiation may give some histological change to pulp tissue, ultratine structure investigation would find the changes in future. 2) In clinical experiment, of 61 cases, the findings showing remarkable effective, effective, and non-effective were 10(16%), 29(48%), and 22(36%) cases, respectively. Though the laser irradiation yielded immediate effect, pain returned in some cases. This uncertain clinical results suggested further study on informations of dentin hypersensitivity to get higher clinical reliability.

最近的研究表明，二极管激光照射对牙本质超敏反应的治疗作用。但是，效果系统仍然无法解决。因此，尚未详细定义疾病辐射的条件和适应症，从而降低了激光治疗的疼痛临床可靠性。该研究旨在检查激光辐射通过激光辐照的组织病理学变化，以了解效果的机制，以了解效果的机制。在30MW上进行了直接的sTrubal of toct。 Wistar大鼠使用Ga-al-As二极管激光器（<lambda>：830nm，Osada Electric Co.）。辐照后2周处死大鼠，并在光学显微镜下常规检查组织病理学。还对患有牙齿过敏的患者进行了临床检查。 1）在这项研究中，纸浆组织的组织病理学表现未发现差异。由于激光辐射因疼痛的损失可能会使纸浆组织的组织学变化一些，因此摩尔结构的研究将发现未来的变化。 2）在临床实验中，有61例表现出显着有效，有效和无效的发现分别为10（16％），29（48％）和22例（36％）病例。尽管激光照射产生了立即的作用，但在某些情况下，疼痛恢复了。这种不确定的临床结果表明，进一步研究了牙本质超敏反应的信息，以获得更高的临床可靠性。