Studies on Dermatoses Caused by Crops Cultivation and its Prevention

农作物种植引起的皮肤病及其防治研究

• 批准号: 62570233
• 负责人: MATSUSHITA Toshio
• 金额: $ 0.96万
• 依托单位: Kagoshima University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1987
• 资助国家: 日本
• 起止时间: 1987 至 1988
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-62570233/
• 关键词: Okra (Hibiscus esculentus L.); Occupational dermatoses; Patch test; 皮膚アレルギー

Epidemiological surveys on occupational dermatoses in farmers growing okra (Hibiscus esculentus L.) and related experimental studies were undertaken.From the field survey over a period of two years, the incidence rates of dermatoses suffering from okra growing were considerably high (46.3-53.9%), and if workers are engaged in the work without effective protective gloves and clothes, nearly all persons are assumed to be suffered from dermatoses following okra farming.Among 118 subjects tested, 16(13.6%) were reacted with okra components by patch testing and okra workers showed relatively higher positive rate (15.7%) than the others (6.9%).By experimental studies using guinea pigs, the components of okra indicated relatively high potency of primary irritating reactions, but not the allergic and phototoxic reaction.Based on those data with epidemiological observations, the mechanism of dermatoses due to okra working were estimated to be consist of the following three effects; (1) mechanical reactions caused by direct contact to a large quality of okra, (2) primary irritating reactions to okra components, and (3) allergic reaction with okra components.Some proposals for effective preventive procedures against okra dermatoses were also examined and discussed.

对种植秋葵（Hibiscus esculentus L.）的农户进行了职业性皮肤病的流行病学调查和相关实验研究。从两年多的现场调查来看，种植秋葵的皮肤病发病率相当高（46.3-53.9%），如果工人在没有有效防护手套和衣服的情况下从事工作，几乎所有人员都可能患上职业性皮肤病。 118 名受试者中，有 16 人（13.6%）通过斑贴试验对秋葵成分产生反应，秋葵工人的阳性率（15.7%）高于其他人（6.9%）。通过使用豚鼠的实验研究，秋葵成分显示出相对较高的原发性刺激反应效力，但没有过敏和光毒性反应。 根据流行病学观察，秋葵作用引起皮肤病的机制估计包括以下三种作用； （1）直接接触大量秋葵引起的机械反应，（2）对秋葵成分的原发性刺激反应，以及（3）对秋葵成分的过敏反应。还检查和讨论了一些针对秋葵皮肤病的有效预防措施的建议。

项目成果

松下敏夫: 産業医学. 30. 724 (1988)

松下敏夫：工业医学。30. 724 (1988)

Matsushita T.: "Skin Lesions in Workers Growing Okra" Journal of Japanese Association of Rural Medicine. 36. 318-319 (1987)

Matsushita T.：“种植秋葵的工人的皮肤损伤”日本农村医学协会杂志。

松下敏夫: 産業医学.

松下敏夫：工业医学。

Matsushita T.: "The Occurrence and Prevention of Skin Lesions Caused by Okra Growing" Japanese Journal of Industrial Health. 30. 724 (1988)

松下 T.：“秋葵生长引起的皮肤损伤的发生和预防”日本工业健康杂志。

萬田芙美: 日本農村医学会雑誌. 37. 190-191 (1988)

Fumi Manda：日本农村医学学会杂志 37. 190-191 (1988)。