The heterogeneity of various Porphyromonas gingivalis strains to adherence and invasive.

牙龈卟啉单胞菌与人类成人牙周炎有关。该生物体已被证明附着在胶原蛋白上，而胶原蛋白是牙龈组织的主要成分。此外，我们发现牙龈卟啉单胞菌菌株与胶原蛋白包被的透明质酸的附着存在明显的异质性。附着在口腔组织上的无毒株比龈沟内的毒力株多。我们还阐明，牙龈卟啉单胞菌菌株对十六烷的吸附与其附着在羟基磷灰石表面上形成的拼贴物上的数量之间存在总体相关性。我们的研究证明，菌株疏水性的差异可能是由于菌毛的差异造成的，菌毛似乎能够附着在胶原蛋白包被的透明质酸上。另一方面，无论毒力如何，囊泡都具有粘附到薄膜或胶原包覆的羟基磷灰石上的粘附性。

Porphyromonas gingivalis has been associated with adult periodontitis in human. The organism has been shown to attach to collagen which is major component gingival tissue. Moreover, we found that there were clear heterogeneity among P. gingivalis strains in their attachment to collagen coated HA. Avirulence strains adherent to oral tissue much than virulence strains in gigival sulcus. We have also clarified that an overall corelation was noted between the adsorption of strains P. gingivalis to hexadecane and their numbers which attached to collage formed on hydroxyapatite surfaces. Our study has proved the evidence that the difference in hydrophobic properties of strains may be due to difference of fimbriae which has appeared to be capable of attachment to collagen coated HA. On the other hand, vesicles have the adhesion which were adherent to pellicle or collagen coated hydropxyapatite regardless of virulence.