Study on Biocompatible Adhesive Restorative Materials

本项目以“生物相容性胶粘剂修复材料的研究”为主题，部分资金由文武所国际科学研究计划提供的为期3年的资助。为了开发新型的生物相容性和黏附性腔衬和修复材料，进行了以下广泛的研究。新型粘接腔衬- II类修复体微渗漏研究一种新型简化粘接修复材料-剪切结合强度及边际微渗漏试验一种新型光活化释氟衬板汞合金修复体新型光活化释氟衬板：微渗漏研究一种新型光活化复合材料：剪切结合强度及微渗漏一种新型光活化胶腔衬板新型粘接剂根面修复材料的体外结合强度与微渗漏研究新型粘接剂根面修复材料的体外微渗漏研究光活化衬骨水泥的酸性与牙本质涂片层的去除实验牙洞衬里的氟化物释放实验牙洞衬里对牙本质的氟吸收牙本质表面对氟吸收的耐酸性牙本质表面对新型光活化氟释放衬里的反应牙体对新型光活化氟释放衬里的反应上述研究表明，新设计的实验光固化胶粘剂腔衬和修复材料与商业产品相比，具有更高的边际泄漏和剪切结合强度，并且在动物实验中表现出高氟释放，高牙本质对氟的吸收，提高牙本质的耐酸能力和良好的生物相容性。这些研究已经完成，并在一些科学会议上发表，其中一些已经发表在科学期刊上，但其余的正在进行中，将在不久的将来发表。

This project, undertaken to perform "Study on Biocompatible Adhesive Restorative Materials", was funded in part by a 3-year grant in aid from the Monbusho International Scientific Research Program.With an eye to developing new types of biocompatible and adhesive cavity liners and restorative materials, extensive research was undertaken as follows.A New Adhesive Cavity Liner-Microleakage Study in Class II Restorations-A new simplified adhesive restorative material-Shear bond strength and marginal microleakage tests-A New Light-activated Fluoride Releasing LinerA New Light-activated Fluoride Releasing Liner for Amalgam Restorations :A Microleakage StudyA new light-activated adhesive composite : shear bond strength and microleakageA new light-activated adhesive cavity liner : an in vitro bond strength and microleakage studyNew Adhesive Root Surface Restorative Material-An In Vitro Microleakage Study-Acidity of Light-activated Lining Cements and Removal of Dentin Smear LayerFluoride release from experimental cavity linerFluoride uptake into dentin from experimental cavity linerAcid resistance of the fluoride uptake dentin surfacePulpal response to a new light-activatedFluoride releasing linerPulpal response to a new light-activatedAdhesive filling materialBy the above-mentioned studies, it was clarified that the newly designed experimental light-cured adhesive cavity liners and restorative materials showed superior marginal leakage and shear-bond strength comparing with commercial products and that they showed high fluoride release, high fluoride uptake by dentin, the increase of dentin acid resistance and superior biocompatibility on animal experiments.The studies were already finished and presented on some scientific meeting, and some of them were already published on the scientific journals, but the remainder are in progress, to be published in the near future.