Assessment of Vital Age in Japanese Adult Men and its Validity.

日本成年男性的生命年龄评估及其有效性。

• 批准号: 03680102
• 负责人: TANAKA Kiyoji
• 金额: $ 1.09万
• 依托单位: University of Tsukuba
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1991
• 资助国家: 日本
• 起止时间: 1991 至 1993
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03680102/
• 关键词: Senescence; Aging; Biological Age; Vital Age; CHD; 中高年; 運動療法; 健康度; 有酸素性運動; 高血圧

We have recently developed a useful equation for estimating vital age (VA) or the so-called biological age of Japanese men, which consists of 10 predictors based on the assessment of various physiological factors measured not only during a state of rest but also during exercise. In general, however, any equations developed in a certain population have the disadvantage of population-specificity. The population-specificity may be due to the multicollinearity of the independent variables, which causes errors when the equations are applied to groups with different multivariate structures of the independent variables. The original analysis provides evidence of an equation's validity , but the strongest evidence is obtained with cross-validation research. The purpose of this study was to determine the cross-validity of VA as a sensitive index of physical health and/or aging status from both the cross-sectional and longitudinal standpoints. Analyzes of the data indicated that there was no significant difference between chronological age (CA : 56.6(〕SY.+-.〔)7.9 yr) and VA (56.1(〕SY.+-.〔)9.9 yr) in the normal men (n=42), while the mean VA (65.1(〕SY.+-.〔)10.9 yr ; 48.7-86.2 yr) of male patients with coronary heart disease (n=22) was significantly lower than their CA (56.4(〕SY.+-.〔)8.9 yr ; 41-70 yr). Correlations between VA's and CA's were r=0.76 in apparently healthy men and preintervention r=0.62 in CHD patients. We reiterate that VA could be a valid index of physical health and/or aging status.

我们最近开发了一个有用的公式，用于估计日本男性的生命年龄(VA)或所谓的生物年龄，它由10个预测因子组成，该公式不仅基于对各种生理因素的评估，而且不仅在休息状态下测量，而且在运动期间也测量。然而，一般而言，在特定种群中发展的任何方程都有种群专一性的缺点。这种群体特异性可能是由于自变量的多重共线性，当方程应用于自变量具有不同多变量结构的群体时，这会导致误差。最初的分析提供了方程有效性的证据，但最有力的证据是通过交叉验证研究获得的。本研究的目的是从横断面和纵向两个角度确定VA作为身体健康和/或老龄化状况的敏感指标的交叉效度。结果表明，正常男性(n=42)的平均年龄(CA：56.6sy.+-7.9岁)与VA(56.1sy.+-9.9岁)无显著差异，而男性冠心病患者(n=22)的VA(65.1sy.+-10.9岁；48.7-86.2岁)显著低于CA(56.4sy.+-8.9岁)；41-70岁)。健康男性VA与CA的相关系数r=0.76，冠心病患者干预前的相关系数r=0.62。我们重申，VA可以作为身体健康和/或衰老状态的有效指标。

项目成果

田中 喜代次,松浦 義行,浅野 勝己,松田 光生,中塘 二三生: "CHD危険因子に基づく活力年齢ー成人男性用の推定式ー" 動脈硬化.

Kiyoji Tanaka、Yoshiyuki Matsuura、Katsumi Asano、Mitsuo Matsuda、Fumio Nakatsuma：“基于 CHD 危险因素的生命年龄 - 成年男性的估计公式”动脉硬化。