Perioperative management in clinical liver traus plantation
Perioperative management in clinical liver traus plantation
批准号:
04044098
负责人:
YAMAOKA Yoshio
金额:
$15.36万
依托单位国家:
日本
项目类别:
Grant-in-Aid for international Scientific Research
财政年份:
1992
资助国家:
日本
项目状态:
已结题
起止时间:
1992 至 1993
中文摘要
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英文摘要
Perioperative management in clinical liver transplantationHistological changes comparing with energy metabolic changes in the rejection state after liver transplantation have not ever studied. In this plan, we have tried the MTT assay of lymphocyte comparing with the changes in arterial ketone body ratio (AKBR) which reflects the energy state of the liver mitochondria after liver transplantation in Hannover Medical Center. The activity of MTT decreased not only in the rejection state but also in the infectious state after liver transplantation. Therefore, MTT assay can not be good indicator of the rejection. However, in the patient with critically decreased in AKBR the MTT activity also decreased.As the collaboration study we have been evaluating measuring the saturation ratio of hemoglobin through the liver graft just after reperfusion using the MCPD method.
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N.Ozaki: "Postoperative recovery of mitochondrial function of human liver graft procured and preserved with University of Wisconsin(UW)solution" Transplant.Int.3. 128-132 (1990)
N.Ozaki:“用威斯康星大学 (UW) 解决方案获得和保存的人肝移植物的线粒体功能术后恢复”Transplant.Int.3。
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N.Ozaki: "Postoperative recovery of mitochondria function of human liver graft procured and preserved with University of Wisconsin (UW) Solution" Transplant.Int. 3. 128-132 (1990)
N.Ozaki:“使用威斯康星大学 (UW) 解决方案获得和保存的人肝移植物的线粒体功能术后恢复”Transplant.Int。
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Y.Yamaoka: "Evaluation of the liver graft before procurement.Significance of arterial ketone body ratio in brain-dead patients" Transplant.Int.3. 78-81 (1990)
Y.Yamaoka:“移植肝移植前的评估。脑死亡患者动脉酮体比率的意义”Transplant.Int.3。
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N.Ozaki: "Changes in energy substrates in relation to arterial ketone body ratio after human orthotopic liver transplantation" Surgery. 113. 403-409 (1993)
N.Ozaki:“人原位肝移植后能量底物与动脉酮体比率的变化”手术。
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Y.Taki: "Significance of arterial ketone body ratio measurement in human liver transplantation" Transplantation. 49. 535-539 (1990)
Y.Taki:“动脉酮体比率测量在人体肝移植中的意义”移植。
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共 6 条
Biological searches for factors interacted with Helicobacter pylori virulence factor OipA
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批准号:24659200
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2012
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负责人:YAMAOKA Yoshio
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依托单位:
Clarification of mechanisms how H. pylori virulence factor OipA produces cytokines
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批准号:22390085
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.99万
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财政年份:2010
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负责人:YAMAOKA Yoshio
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依托单位:
Molecular Epidemiological Studies using Helicobacter pylori
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批准号:22659087
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$1.95万
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财政年份:2010
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负责人:YAMAOKA Yoshio
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依托单位:
The research to establish the orader-made therapy system for hepatocellular carcinoma patients by use of genome-wide microarray database
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批准号:13357013
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$30.45万
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财政年份:2001
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负责人:YAMAOKA Yoshio
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依托单位:
Activation of regeneration capacity of the cirrhotic livers based on the molecular and genetic biology
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批准号:11307022
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$25.96万
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财政年份:1999
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负责人:YAMAOKA Yoshio
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依托单位:
Availability of interlrulkin 12 for gene therapy of hepatoma
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批准号:09044294
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$3.14万
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财政年份:1997
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负责人:YAMAOKA Yoshio
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依托单位:
Moduration of the molecular chaperone activity to increase the safety of extended liver surgery in the damaged liver patients -- challenge by the induction of stress response and heat shock gene transfection --
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批准号:09307026
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$22.78万
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财政年份:1997
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负责人:YAMAOKA Yoshio
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依托单位:
Comparative study of immunological tolerance in the liver transplantation from cadaver and living donor
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批准号:08044278
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$7.3万
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财政年份:1996
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负责人:YAMAOKA Yoshio
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依托单位:
Non-touch isolation hepatectomy and extra-corporeal anticancer therapy for liver tumors-Feedback of surgical technique in living-related partial liver transplantation to liver surgery-
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批准号:07407035
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$13.7万
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财政年份:1995
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负责人:YAMAOKA Yoshio
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依托单位:
Comperative study in the viability of the liver graft harvested from cadaver and living donor, evaluated by assessment of tissue oxygenation in sinusoid and oxidation of hepatocyte
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批准号:06044127
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$15.1万
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财政年份:1994
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负责人:YAMAOKA Yoshio
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依托单位:
Surgical Treatment for Hepatic Malignancy, In Situ and Ex Situ
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批准号:03454318
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.22万
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财政年份:1991
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负责人:YAMAOKA Yoshio
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依托单位:
Hepatic Resection Using in-situ Cold Perfusion Under Total Vascular Exclusion
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批准号:01480325
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.42万
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财政年份:1989
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负责人:YAMAOKA Yoshio
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依托单位:
海外基金