Biological searches for factors interacted with Helicobacter pylori virulence factor OipA
Biological searches for factors interacted with Helicobacter pylori virulence factor OipA
批准号:
24659200
负责人:
YAMAOKA Yoshio
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
It is known that Helicobacter pylori has various virulence factors. I hypothesized that severe disease was occurred by multiple effects of virulence factors. In this study, I succeeded in purification of OipA protein, which caused gastric inflammation. It became clear that OipA protein constituted a protein super complex with BabA protein, had ability to adhesion with stomach cells, in H. pylori outer membrane.In the near future, human stomach protein(s) interacting with OipA protein will be identified. Furthermore, the mechanism will be revealed that OipA protein collaborate with the other virulence factors.
期刊论文(77)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
DOI:
10.1111/1751-2980.12054
发表时间:
2013-07
期刊:
Journal of digestive diseases
影响因子:
3.5
作者:
[Shiota S, Suzuki R, Yamaoka Y]
通讯作者:
Yamaoka Y
Roles of virulence factors of Helicobacter pylori: OipA and DupA
幽门螺杆菌毒力因子:OipA 和 DupA 的作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[中山順之, 百瀬文隆, 森川裕子, Yamaoka Y]
通讯作者:
Yamaoka Y
アジア諸国におけるヘリコバクター・ピロリの遺伝子型:沖縄特異型を含めて
亚洲国家幽门螺杆菌基因型:包括冲绳特有型
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[松尾祐一, 城戸康年, 山岡吉生, Yamaoka Y., Yamaoka Y., Yamaoka Y., 山岡吉生, Yamaoka Y., Yoshio Yamaoka, Yoshio Yamaoka, Yoshio Yamaoka, Yoshio Yamaoka, Yoshio Yamaoka, Seiji Shiota, Trang TH Tran, 山岡吉生, Yamaoka Y., Osamu Matsunari, Seiji Shiota, Tran T Binh, Varocha Mahachai, Tomohisa Uchida, Yamaoka Y., Yamaoka Y., 山岡吉生, 山岡吉生, 山岡吉生]
通讯作者:
山岡吉生
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[松尾祐一, 城戸康年, 山岡吉生, Yamaoka Y., Yamaoka Y., Yamaoka Y., 山岡吉生, Yamaoka Y., Yoshio Yamaoka, Yoshio Yamaoka, Yoshio Yamaoka, Yoshio Yamaoka, Yoshio Yamaoka, Seiji Shiota, Trang TH Tran, 山岡吉生, Yamaoka Y., Osamu Matsunari, Seiji Shiota, Tran T Binh, Varocha Mahachai, Tomohisa Uchida, Yamaoka Y., Yamaoka Y., 山岡吉生, 山岡吉生, 山岡吉生, 山岡吉生, Yoshio Yamaoka, Yoshio Yamaoka, 山岡吉生, Yoshio Yamaoka]
通讯作者:
Yoshio Yamaoka
DOI:
10.1099/jmm.0.060905-0
发表时间:
2013-10-01
期刊:
JOURNAL OF MEDICAL MICROBIOLOGY
影响因子:
3
作者:
[Shiota, Seiji, Mahachai, Varocha, Yamaoka, Yoshio]
通讯作者:
Yamaoka, Yoshio
共 55 条
Clarification of mechanisms how H. pylori virulence factor OipA produces cytokines
-
批准号:22390085
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$7.99万
-
财政年份:2010
-
负责人:YAMAOKA Yoshio
-
依托单位:
Molecular Epidemiological Studies using Helicobacter pylori
-
批准号:22659087
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$1.95万
-
财政年份:2010
-
负责人:YAMAOKA Yoshio
-
依托单位:
The research to establish the orader-made therapy system for hepatocellular carcinoma patients by use of genome-wide microarray database
-
批准号:13357013
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$30.45万
-
财政年份:2001
-
负责人:YAMAOKA Yoshio
-
依托单位:
Activation of regeneration capacity of the cirrhotic livers based on the molecular and genetic biology
-
批准号:11307022
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$25.96万
-
财政年份:1999
-
负责人:YAMAOKA Yoshio
-
依托单位:
Moduration of the molecular chaperone activity to increase the safety of extended liver surgery in the damaged liver patients -- challenge by the induction of stress response and heat shock gene transfection --
-
批准号:09307026
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$22.78万
-
财政年份:1997
-
负责人:YAMAOKA Yoshio
-
依托单位:
Availability of interlrulkin 12 for gene therapy of hepatoma
-
批准号:09044294
-
项目类别:Grant-in-Aid for international Scientific Research
-
资助金额:$3.14万
-
财政年份:1997
-
负责人:YAMAOKA Yoshio
-
依托单位:
Comparative study of immunological tolerance in the liver transplantation from cadaver and living donor
-
批准号:08044278
-
项目类别:Grant-in-Aid for international Scientific Research
-
资助金额:$7.3万
-
财政年份:1996
-
负责人:YAMAOKA Yoshio
-
依托单位:
Non-touch isolation hepatectomy and extra-corporeal anticancer therapy for liver tumors-Feedback of surgical technique in living-related partial liver transplantation to liver surgery-
-
批准号:07407035
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$13.7万
-
财政年份:1995
-
负责人:YAMAOKA Yoshio
-
依托单位:
Comperative study in the viability of the liver graft harvested from cadaver and living donor, evaluated by assessment of tissue oxygenation in sinusoid and oxidation of hepatocyte
-
批准号:06044127
-
项目类别:Grant-in-Aid for international Scientific Research
-
资助金额:$15.1万
-
财政年份:1994
-
负责人:YAMAOKA Yoshio
-
依托单位:
Perioperative management in clinical liver traus plantation
-
批准号:04044098
-
项目类别:Grant-in-Aid for international Scientific Research
-
资助金额:$15.36万
-
财政年份:1992
-
负责人:YAMAOKA Yoshio
-
依托单位:
Surgical Treatment for Hepatic Malignancy, In Situ and Ex Situ
-
批准号:03454318
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.22万
-
财政年份:1991
-
负责人:YAMAOKA Yoshio
-
依托单位:
Hepatic Resection Using in-situ Cold Perfusion Under Total Vascular Exclusion
-
批准号:01480325
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.42万
-
财政年份:1989
-
负责人:YAMAOKA Yoshio
-
依托单位:
国内基金
海外基金
登录
查看更多内容
靶向CDH1 调控相关的miRNA 在早发性胃癌中的作用机制及诊断价值研究
-
批准号:ZCLMRY26H2003
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:张毅敏
-
依托单位:
基于“痞积转化”理论探究网果酸模通过PI3K/Akt通路调控巨噬细胞极化平衡抑制胃癌的分子机制
-
批准号:JCZRLH202601927
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:
-
依托单位:
MerTK调控肿瘤相关巨噬细胞M2极化介导胃癌进展和免疫耐药作用和机制研究
-
批准号:JCZRLH202600496
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:
-
依托单位:
开发和临床验证一种基于血清细胞外囊泡circRNA的人工智能机器学习算法用于构建胃癌早期预测模型
-
批准号:JCZRMS202601543
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:
-
依托单位:
CTSL调控巨噬细胞极化与上皮间质化促进胃癌腹膜转移的机制
-
批准号:JCZRLH202601993
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:
-
依托单位:
《子午流注择时中医护理技术对胃癌化疗患者癌因性疲乏的干预效果及方案优化研究》
-
批准号:2026JJ81371
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:曾一鸣
-
依托单位:
Circ_0009594通过招募HNRNPA1上调NRF2表达抑制胃癌铁死亡的作用与机制研究
-
批准号:2026JJ82174
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:肖华
-
依托单位:
基于多重组学液体活检术的胃癌人工智能精准诊疗体系构建及实践
-
批准号:2026JJ81931
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:田继东
-
依托单位:
YBX1介导的HOXA9 mRNA稳定性影响c-MYC转录在胃癌进展中的机制研究
-
批准号:2026JJ82359
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:卢太亮
-
依托单位:
幽门螺杆菌诱导中性粒细胞CXCL8-C3AR1轴促进胃癌免疫逃逸的机制研究
-
批准号:2026JJ82697
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:邹品衡
-
依托单位: