Topologically chiral and cycloenantiomeric catenanes, rotaxanes and pretzelanes: New hybrid types and their stereoselective synthesis

拓扑手性和环对映体索烷、轮烷和椒盐烷：新的杂化类型及其立体选择性合成

• 批准号: 5260744
• 负责人: Professor Dr. Fritz Vögtle (†)
• 金额: --
• 依托单位: Vant Hoff Institute for Molecular Sciences
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2000
• 资助国家: 德国
• 起止时间: 1999-12-31 至 2004-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/5260744?language=en
• 关键词: Topologically; chiral; cycloenantiomeric; catenanes; rotaxanes

By combining characteristic supramolecular buildung blocks, synthetic tricks, and the stereochemical know-how of some leading European groups in the present project it will be possible to prepare new catenanes, rotaxanes, and more complex supramolecular species showing new stereochemical features and exhibiting new material properties. In the foreground are topologically chiral species like catenanes and pretzelanes of a mixed hybrid type as well as cycloenantiomeric and cyclodiastereomeric rotaxanes which contain at the same time phenanthroline- and amide-units in their skeleton. They will be assembled to larger chiral scaffolds and used for further template reactions. Their synthesis will be for the first time carried out stereoselectively. From these studies new knowledge of supramolecular syntheses, of topological chirality and of complex supramolecules and of structure-chiroptics dependendies is expected to emerge, as well as new insights into mechanical bonding of molecules.

通过结合本项目中一些领先的欧洲小组的特征超分子构建块，合成技巧和立体化学知识，将有可能制备新的索烃，轮烷和更复杂的超分子物种，显示新的立体化学特征和新的材料性能。在前景是拓扑手性物种，如索烃和pretzelanes的混合杂交型，以及环对映体和环非对映体轮烷，其中含有在同一时间菲咯啉和酰胺单位在其骨架。它们将组装成更大的手性支架并用于进一步的模板反应。它们的合成将首次立体选择性地进行。从这些研究中，新的知识的超分子合成，拓扑手性和复杂的超分子和结构手性dependendies预计将出现，以及新的见解到分子的机械键合。