Novel disinfection to combat antibiotic resistance

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Control of antimicrobial resistance in water is critical. Disinfection in water and wastewater treatment plants is a vital barrier against antibiotic resistant bacteria (ARB); however, it is less effective in controlling- and may even facilitate the spread of antibiotic resistance genes (ARGs). This project aims to comprehensively investigate the effectiveness of widely-used disinfection processes in controlling ARB/ARGs, determine the underlying mechanisms, and identify optimal treatment conditions. This project also aims to develop a novel, cost-effective and environmentally friendly disinfection process for efficient ARGs destruction, thus significantly strengthening Australia’s capacity to prevent the spread of antibiotic resistance.