Intra-, and Extracranial Vasodilation Elicited by Lingual and Facial Nerve Stimulation in Anesthetized Cats

麻醉猫的舌神经和面神经刺激引起的颅内和颅外血管舒张

• 批准号: 07672151
• 负责人: SATO Minoru
• 金额: $ 1.6万
• 依托单位: TOHOKU UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07672151/
• 关键词: Cats; Parasympathetic reflex vasodilation; cerebrocortical blood flow; common carotid artery; lip blood flow; palate blood flow; 顔面神経刺激; 下唇・口蓋血流; 顔面・口腔領域の血流; 脳血流; 副交感神経; 血管拡張; レーザードップラー血流系

The effects were compared of electrical stimulation of the central cut end of the lingual nerve and the peripheral cut end of the facial (VIIth cranial) nerve root on ipsilateral blood flow in lower lip, palate, frontal cerebral cortex and common carotid artery (CCA) in a-chloralose-urethane anesthetized, vago-sympathectomized cats. The vasomotor responses to lingual nerve and facial nerve stimulation were very similar to each other in lip, palate, and CCA,but in the frontal cerebral cortex lingual nerve stimulation did not induce any blood flow increase, while facial nerve stimulation caused only a slight increase. These results suggest that there is no somato-parasympathetic reflex vasodilator mechanism in the frontal cerebral cortex, and that changes be in CCA blood flow do not be taken to indicative of blood flow changes in cerebrocortical blood flow.

本文比较了电刺激舌神经中央切断端和面神经根外周切断端对氯醛糖-乌拉坦麻醉猫同侧下唇、腭、大脑额叶皮质和颈总动脉血流的影响。舌神经和面神经刺激的血管反应在唇、腭和CCA中彼此非常相似，但在额叶大脑皮层中，舌神经刺激没有引起任何血流量增加，而面神经刺激仅引起轻微增加。这些结果表明，在额叶大脑皮层中不存在躯体-副交感神经反射血管扩张机制，并且CCA血流的变化不被认为是大脑皮层血流变化的指示。

项目成果

和泉博之: "Bloodflow increases in common carotid artery,lower lip and palate elicited lingual nerve stimulation in anesthetized cats." Journal of the Autonomic Nervous System. 62. 167-173 (1997)

Hiroyuki Izumi：“颈总动脉、下唇和上颚的血流增加引起麻醉猫的舌神经刺激。”《自主神经系统杂志》62. 167-173 (1997)。

和泉博之: "Effect of inhalation anesthetics on the parasympathetic reflex vasodilation in lower lip and palate of the cat." American Journal of Physiology. (印刷中).

Hiroyuki Izumi：“吸入麻醉剂对猫下唇和上颚副交感神经反射血管舒张的影响”美国生理学杂志（正在出版）。

H Izumi, M Sato, K Karita and N Iwatsuki: "Bloodflow increases in common carotid artery, lower lip and palate elicited lingual nerve stimulation in anesthetized cats." JANS. 62. 167-173

H Izumi、M Sato、K Karita 和 N Iwatsuki：“颈总动脉、下唇和上颚的血流量增加，引起麻醉猫的舌神经刺激。”

和泉 博之: "Effect of inhalation anesthetics on the parasympathetic reflex vasodilation in lower lip and palate of the cat." American Journal of Physiology. (印刷中).

Hiroyuki Izumi：“吸入麻醉剂对猫下唇和上颚副交感神经反射血管舒张的影响”美国生理学杂志（正在出版）。

Hiroshi Izumi, Yutaka Ito, Minoru Sato, Keishiro Karita and Naofumi Iwatsuki: "Effect of inhalation anesthetics on the parasympathetic reflex vasodilation in lower lip and palate of the cat." Am. J.Physiol.(in press).

Hiroshi Izumi、Yutaka Ito、Minoru Sato、Keishiro Karita 和 Naofumi Iwatsuki：“吸入麻醉剂对猫下唇和上腭副交感神经反射性血管舒张的影响。”