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EPIDEMIOLOGICAL STUDY ON GREEN TER DRINKING AND SERUM LIPIDS

EPIDEMIOLOGICAL STUDY ON GREEN TER DRINKING AND SERUM LIPIDS
绿色饮料与血清脂质的流行病学研究
批准号:
08457116
负责人:
KONO Suminori
金额:
$1.47万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
1996
资助国家:
日本
项目状态:
已结题
起止时间:
1996 至 1998

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中文摘要
翻译
一个包含7,637名48-59岁男性自卫官的数据库是通过将2500多名男性的数据添加到之前接受自卫队(SDF)退休前健康检查的男性数据集而创建的。该数据库包括关于生活方式因素的横截面信息和全面的医疗数据;关于吸烟、饮酒、绿色茶消费、咖啡消费和整个调查期间常见的10种其他食物的信息。医学数据包括血脂、血清肝酶、血清尿酸、75克口服葡萄糖耐量试验结果、胆囊超声检查和结肠镜检查结果。我们调查了7,391名男性的绿色茶摄入量与血清总胆固醇、高密度脂蛋白胆固醇和甘油三酯浓度的关系,排除了那些服用降血脂药物和其他药物的男性。调整后对住院时间、研究年限、年龄、SDF中的等级、吸烟、饮酒、体重指数、糖耐量状态进行测定 关于我们 通过75克口服葡萄糖耐量试验和咖啡摄入量。每天饮用0、1-3、4-6、7-9和10+杯绿色茶的男性血清总胆固醇的平均浓度分别为201.9、199.4、197.3、200.0和196.3 mg/dl(趋势p = 0.0007)。饮用绿色茶与血清高密度脂蛋白胆固醇或甘油三酯没有可测量的相关性。牛奶、面包、豆浆汤、生蔬菜的摄入量对血清总胆固醇水平的变化有显著或接近显著的影响。在对这些饮食变量进行额外调整后,每天喝一杯绿色茶与血清总胆固醇浓度降低0.39 mg/dl(95%置信区间0.21-0.80)相关。饮用咖啡与血清总胆固醇、高密度脂蛋白胆固醇或甘油三酯水平没有实质性关系。我们还调查了饮用绿色茶以外的生活方式因素与健康相关生物学参数之间的关系。研究发现,喝咖啡与血清肝酶、血清尿酸水平降低和血压降低有关。喝绿色茶没有表现出这样的联想。少
英文摘要
A database of 7,637 male self-defense officials aged 48-59 was created by adding data of more than 2500 men to the previous data set of men receiving a preretirement health examination of the Self Defense Forces (SDF). This database included cross-sectional information on lifestyle factors and comprehensive medical data ; information on smoking, alcohol use, green tea consumption, coffee consumption, and 10 other food items in common throughout the survey period. Medical data included serum lipids, serum liver enzymes, serum uric acid, result of a 75-g oral glucose tolerance test, findings of gallbladder ultrasonography and colonoscopy. We investigated the relationship of green tea consumption with serum concentrations of total cholesterol, HDL cholesterol, and triglycerides in 7,391 men excluding those under hypolipidemic medication and others. After adjustment for hospital, study period, age, rank in the SDF, smoking, alcohol use, body mass index, glucose tolerance status determined … More by a 75-g oral glucose tolerance test, and coffee consumption. Mean concentrations of serum total cholesterol among men consuming 0, 1-3, 4-6, 7-9, and 10+ cups of green tea per day were 201.9, 199.4, 197.3, 200.0, and 196.3 mg/dl, respectively (trend p = 0.0007). Green tea consumption was not measurably related to either serum HDL cholesterol or triglycerides. The consumption of milk, bread for breakfast, soy paste soup, and raw vegetables each made a significant or nearly significant contribution to the variation of serum total cholesterol levels. After additional adjustment for these dietary variables, drinking one cup of green tea per day was associated with a decrease of 0.39 mg/dl (95% confidence interval 0.21-0.80) in serum concentrations of total cholesterol. Coffee consumption was not materially related to serum levels of total cholesterol, HDL cholesterol or triglycerides.We also investigated the relation between lifestyle factors other than green tea drinking and health-related biological parameters. Coffee drinking was found to be associated with lower levels of serum liver enzymes, serum uric acid, and lower blood pressure. Green tea drinking did not show such associations. Less
期刊论文(17)
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会议论文
古野 純典: "緑茶飲用と血液コレステロール" 臨床栄養. 90(4)(発表予定). (1997)
Junnori Furuno:“绿茶饮用与血液胆固醇”《临床营养学》90(4)(待出版)。
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古野 純典: "Behavioral correlates of plasma sex hormones and their relationship with plasma Lipids and Lipoproteins in Japanese mem" Atherosclerosis. 130. 37-44 (1997)
Junnori Furuno:“日本记忆中血浆性激素的行为相关性及其与血浆脂质和脂蛋白的关系”动脉粥样硬化。
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通讯作者:
Kono S, et al: "Relation of green tea consumption to serum lipids and lipoproteins in Japanese men"Journal of Epidemiology. 6. 128-133 (1996)
Kono S 等人:“日本男性绿茶摄入量与血清脂质和脂蛋白的关系”流行病学杂志。
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通讯作者:
古野純典: "緑茶飲用と血液コレステロール"臨床栄養. 90. 540 (1997)
Junnori Furuno:“绿茶饮用与血液胆固醇”《临床营养学》90. 540 (1997)。
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16
    Molecular epidemiological study on lifestyles, inflammation and diabetes mellitus in a population-based cohort
    • 批准号:
      21249044
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $29.2万
    • 财政年份:
      2009
    • 负责人:
      KONO Suminori
    • 依托单位:
    Molecular epidemiology on obesity and colorectal carcinogenesis
    • 批准号:
      19390175
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $8.9万
    • 财政年份:
      2007
    • 负责人:
      KONO Suminori
    • 依托单位:
    Molecular Epidemiology on insulin-like growth facto (IGF) and colorectal adenomas
    • 批准号:
      15390204
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.54万
    • 财政年份:
      2003
    • 负责人:
      KONO Suminori
    • 依托单位:
    海外基金