Human osteoprogenitor cells : osteoblastic phenotype and osteoblastic activity
Human osteoprogenitor cells : osteoblastic phenotype and osteoblastic activity
批准号:
08457383
负责人:
TAKAHASHI Hideaki
金额:
$4.29万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
1996
资助国家:
日本
项目状态:
已结题
起止时间:
1996 至 --
中文摘要
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英文摘要
In osteoporosis, bone formation declines with age and it may result from a decrease in the number and/or activity of osteoprogenitor cells.1. Osteoprogenitor cells are present in human iliac bone marrow.2. The number of ALP-positive CFU-F declines with age, suggesting its association with skeletal growth.3. BMP and other bone matrix related proteins mRNA are expressed.These results indicated that bone marrow stromal cells differentiate to osteoblasts.
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Endo N., et al.: "Human osteoprogenitor cells express BMP1-6 and its differentiation is stimulated by BMP-2." J.Bone Miner.Res.11. s257 (1996)
Endo N. 等人:“人类骨祖细胞表达 BMP1-6,并且 BMP-2 刺激其分化。”
DOI:
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影响因子:
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作者:
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通讯作者:
Endo N., et al.: "Human osteoprogenitor cells express BMP1-6 and its differentiation is stimulated by BMP-2." J.Bone Miner.Res.11. S257- (1996)
Endo N. 等人:“人类骨祖细胞表达 BMP1-6,并且 BMP-2 刺激其分化。”
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
N. Endo,et al.: "Human Osteoprogenitor Cells Express BMP 1-6 and Its Differentiation is Stimulated by BMP-2" Journal of Bone and Mineral Research. 11. S257 (1996)
N. Endo 等人:“人类骨祖细胞表达 BMP 1-6 及其分化受 BMP-2 刺激”《骨与矿物质研究杂志》。
DOI:
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影响因子:
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作者:
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通讯作者:
Endo N., et al.: "The number of ALP-positive CFU-Fs is one of the indices exhibiting bone-forming activity in the marrowstronal cells" J.J.B.E.R.S.10. 23-25 (1996)
Endo N. 等人:“ALP 阳性 CFU-F 的数量是骨髓基质细胞中表现出骨形成活性的指标之一”J.J.B.E.R.S.10。
DOI:
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发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
Endo N., et al.: "The number of ALP-positive CFU-Fs is one of the indices exhibiting bone-forming activity in the marrow stromal cells." J.J.B.E.R.S.10. 23-25 (1996)
Endo N.等人:“ALP阳性CFU-F的数量是骨髓基质细胞中表现出骨形成活性的指标之一。”
DOI:
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发表时间:
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通讯作者:
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