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The motor control and recruitment of skeletal muscle during eccentric ecercise

离心运动过程中的运动控制和骨骼肌募集

基本信息

批准号：
10680024
负责人：
YOSHIMURA Atsushi
金额：
$ 1.92万
依托单位：
Nagoya Institute of Technology (NIT)
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1998
资助国家：
日本
起止时间：
1998 至 1999
项目状态：
已结题

项目摘要

We investigated the recruitment patterns of intrafusal and extrafusal subtypes in the rat soleus (SOL), extensor digitorum longus (EDL), flexor digitorum superficial (FDS) and extensor digitorum (ED) muscles during downhill running. A rest control and an exercise group of six rats each were prepared. A rest control and an exercise group of six rats each were prepared and each rat was subjected to training (5 days per week) for four weeks. Only the rat of the exercise group carried out a downhill running, an exhaustive 4-min run on a motordriven belt with a speed of 40m/min and down a 6°incline, on the experiment day. Periodic acid Schiff' s stain was used to estimate optically the glycogen content of the semi-serial sections of each fiber subtype which were identified by myosin A TPase staining. Compared with the control group, the glycogen contents after exercise decreased significantly in all extrafusal subtypes of four kind of skeletal muscles. For extrafusal subtypes of SOL and EDL … More which was hind leg, the glycogen decrease of type IIA (intermediate type) in SOL were larger than type I (slow type), and the value of IIA in EDL was larger than type IIB (fast type). In the fore leg, however, in ED the glycogen decrease of type IIB was largest among the extrafufsal subtypes, and in ED non-significant decreased was found in the three types of extrafusal fibers. For intrafusal muscle fibers, the glycogen contents after exercise decreased significantly in all intrafusal subtypes of four kind of skeletal muscles. In SOL and EDL muscle spindles, the glycogen decrease of bag2 (intermediate type) was larger than type bag1 (slow type) either chain (fast type). In ED, the glycogen decrease of bag2 was also larger than chain, but there was non-singnificant decreased among the types of intrafusal fibers in FDS.The results suggest that during downhill running as an eccentric exercise model, the recruitment patters of intrafusal subtypes are not straight forward relation to those of extrafusal subtypes and might be not depend on size principle like a extrasusal subtypes. Less

我们研究了大鼠比目鱼肌（SOL）、趾长伸肌（EDL）、趾浅屈肌（FDS）和趾伸肌（艾德）在下坡跑过程中梭内肌和梭外肌亚型的募集模式。制备了休息对照组和运动组，每组6只大鼠。准备休息对照组和运动组，每组6只大鼠，每只大鼠接受训练（每周5天），持续4周。运动组大鼠在实验当天进行下坡跑，即以40 m/min的速度在6°斜坡上沿电动皮带跑4 min。高碘酸希夫氏染色用于光学估计通过肌球蛋白A T染色鉴定的每种纤维亚型的半连续切片的糖原含量。与对照组相比，运动后四种骨骼肌梭外肌各亚型糖原含量均显著降低。对于SOL和EDL的梭外亚型 ...更多信息 SOL中IIA型（中间型）糖原下降幅度大于I型（慢型），EDL中IIA型糖原下降幅度大于IIB型（快型）。然而，在前肢，艾德型的糖原减少是最大的外梭肌亚型中，和艾德无显着减少被发现在三种类型的梭外纤维。对于梭内肌纤维，运动后四种骨骼肌各肌型肌纤维糖原含量均显著降低。在SOL和EDL肌梭中，bag 2（中间型）的糖原减少量大于bag 1型（慢型）和任一链（快型）。在艾德组，bag 2的糖原减少量也大于chain，而FDS中梭内肌纤维类型间的糖原减少量无显著性差异.结果提示，在下坡离心运动模型中，梭内肌纤维类型与梭外肌纤维类型之间的募集模式并非直接相关，可能不像梭外肌纤维类型那样依赖于尺寸原则.少