权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

DEVELOPMENT OF THE LASER ULTRASONIC MICROMANIPULATOR

激光超声波微操作器的研制

基本信息

批准号：
11650271
负责人：
TAKEUCHI Masao
金额：
$ 2.3万
依托单位：
Tamagawa university
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1999
资助国家：
日本
起止时间：
1999 至 2000
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11650271/
关键词：
ULTRASONICS MANIPULATION SMALL PARTICLE LASER MANIPULATOR RADIATION FORCE 放射力微小計測

项目摘要

Noncontact and nondestructive techniques for manipulation, such as transportation, trapping, and separation of micron-sized particles in liquid, are currently of considerable interest in areas of biotechology and micromachining. Optical tweezers are a known example of noncontact manipulation of small particles. Radiation pressure from laser beams is used. However, trapping is difficult for particles that have a small refractive index or are metallic. Also, the narrow width of optical potential wells is a significant limitation for the continuous manipulation of the small particles. Previously we have proposed ultrasonic micromanipulation (UMM) techniques for micron-sized particles in liquid based on the radiation forces of very-high-frequency (VHF) ultrasound. Using the visual feedback technique we demonstrated two-dimensional manipulation of a polystyrene sphere along a circle and character patterns.In this study, we have developed a new laser ultrasonic micromanipulator (LUMM) in which the acoustic radiation force and optical radiation force are both used as complementary noncontact forces. All experimental LUMM consists of an acoustic leaky wave transducer of center frequency 49 MHz, a Baser diode with a maximum power 5 mW at 675 nm and a biological microscope. Using the LUMM, we have carried out successfully the rapid selection of a specific particle in liquid by the removal of unwanted particles from large number of 12-μm-diameter polystyrene spheres.The LUMM was also used to estimate the horizontal component of the ultrasonic radiation force by using Stokes law and the measured critical velocity at which the trapping is released by mechanically moving particles. Parts of these results are presented in IEEE 2000 Ultrasonics Symposium. The unpublished results will be presented in near future.

非接触和非破坏性的操纵技术，例如液体中微米级颗粒的运输、捕获和分离，目前在生物技术和微机械加工领域引起了相当大的兴趣。光镊是小颗粒的非接触操纵的已知示例。使用来自激光束的辐射压力。然而，对于具有小折射率或为金属的颗粒，捕获是困难的。此外，光学势威尔斯的窄宽度对于小颗粒的连续操纵是显著的限制。此前，我们提出了基于甚高频（VHF）超声辐射力的液体中微米级颗粒的超声微操作（UMM）技术。利用视觉反馈技术实现了对聚苯乙烯球沿着圆周方向和字符图案的二维操作，在本研究中，我们研制了一种新型的激光超声微操作器（LUMM），其中声辐射力和光辐射力都作为互补的非接触力。所有实验LUMM由一个中心频率为49 MHz的声漏波换能器，一个在675 nm处最大功率为5 mW的Baser二极管和生物显微镜组成。利用LUMM，我们成功地实现了从大量直径为12 μ m的聚苯乙烯球中快速选择特定颗粒，并利用Stokes定律和测量的机械运动颗粒释放捕获的临界速度估算了超声辐射力的水平分量。这些结果的一部分在IEEE 2000年超声研讨会。未发表的结果将在不久的将来公布。