Establishment of International Hibakusha's Medical Information Network.

建立国际原爆幸存者医疗信息网络。

基本信息

  • 批准号:
    11794020
  • 负责人:
  • 金额:
    --
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for University and Society Collaboration
  • 财政年份:
    1999
  • 资助国家:
    日本
  • 起止时间:
    1999 至 2000
  • 项目状态:
    已结题

项目摘要

Epidemiological studies including Atomic Bomb survivors and children around Chernobyl suggest that thyroid gland as well as bone marrow seem to be one of the most sensitive organs to the carcinogenic effects of external radiation. Since 1999, the satellite-based telemedicine has been successfully introduced between Nagasaki and Gomel in Belarus, and between Nagasaki and Semipalatinsk in Kazakhstan, respectively. The results of medical assistance are highly evaluated because of increased number of early diagnosis of thyroid cancers and great contribution on surgical treatment for such patients. The exchange programs of researches are aiso useful not only to improve infrastructure of medical knowledge but also to promote mutual understanding among these countries. Now our telemedicine program is undertaken by WHO-SMHF Health Telematics using internet-based telecommunication. Concerning the operated childhood thyroid cancer tissues around Chernobyl, gene rearrangements of ret/PTC subtypes have been reported as a common genetic damage of radiation-associated thyroid cancer. The post-Chernobyl Thyroid Tissues, Nucleic Acids and Data Bank have been just established at the three countries (Minsk, Kiev and Obninsk) as an internationally supported cooperative research resource (http://www.wrl.cam.ac.uk/nisctb), which is now expected to avoid direct competition for limited tissue resources. Owing to such international cooperation, the infrastructure of scientific research on radiation-associated human thyroid carcinogenesis has been established. Finally the two-years project has now paved how we could cooperate and contribute from Nagasaki to the worid but there is a room for improvement, vice verse, how Nagasaki is activated from the world.
包括原子弹幸存者和切尔诺贝利周围儿童在内的流行病学研究表明,甲状腺和骨髓似乎是对外部辐射致癌效应最敏感的器官之一。自1999年以来,分别在白俄罗斯的长崎和戈梅利之间以及哈萨克斯坦的长崎和塞米巴拉金斯克之间成功地采用了卫星远程医疗。由于甲状腺癌的早期诊断数量增加以及对此类患者的手术治疗做出了巨大贡献,医疗援助的结果受到高度评价。研究交流项目不仅有助于改善医学知识的基础设施,而且有助于促进这些国家之间的相互了解。现在,我们的远程医疗计划是由世界卫生组织-SMHF健康电信公司利用基于互联网的电信进行的。关于切尔诺贝利周围手术的儿童甲状腺癌组织,ret/PTC亚型的基因重排已被报道为辐射相关甲状腺癌的常见遗传损伤。切尔诺贝利事故后的甲状腺组织、核酸和数据库刚刚在三个国家(明斯克、基辅和奥布宁斯克)建立,作为一个国际支助的合作研究资源(http://www.wrl.cam.ac.uk/nisctb),现在预计将避免对有限的组织资源的直接竞争。由于这种国际合作,建立了与辐射有关的人类甲状腺癌的科学研究基础设施。最后,为期两年的项目现在已经为我们如何从长崎向世界合作和贡献铺平了道路,但还有改进的余地,反之亦然,长崎如何从世界激活。

项目成果

期刊论文数量(15)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
山下俊一: "チェルノブイリ原発事故後の健康問題"臨床検査. 44・6. 665-667 (2000)
山下俊一:“切尔诺贝利核电站事故后的健康问题” 44・667(2000)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
K. Yokota,et al.: "Evaluation of a telemedicine system for supporting thyroid disease diagnosis. MEDlNFO 2001 V. Patel, et al. (eds)"Amsterdam. 866-869 (2001)
K. Yokota 等人:“支持甲状腺疾病诊断的远程医疗系统的评估。MEDlNFO 2001 V. Patel 等人(编)”阿姆斯特丹。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
N. Takamura,et al.: "Chemobyl-induced radiophobia and the incidence of tuberculosis."Lancet. 356. 257 (2000)
N. Takamura 等人:“Chemobyl 引起的放射恐惧症和结核病的发病率。”柳叶刀。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
V. Braiden,et al.: "Eradication of breast cancer xenografts by hyperthermic suicide gene therapy under the control of the heat shock protein promoter."Human Gene Therapy. 11(10). 2453-2463 (2000)
V. Braiden 等人:“在热休克蛋白启动子的控制下通过高温自杀基因疗法根除乳腺癌异种移植物。”人类基因疗法。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
Y.Sautin, et al.: "Ceramide-induced apoptosis of human thyroid cancer cells resistant to apoptosis by irradiation"Thyroid. 10・9. 734-740 (2000)
Y. Sautin 等人:“神经酰胺诱导的抗辐射细胞凋亡的人甲状腺癌细胞” Thyroid 734-740 (2000)。
  • DOI:
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  • 期刊:
  • 影响因子:
    0
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YAMASHITA Shunichi其他文献

YAMASHITA Shunichi的其他文献

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{{ truncateString('YAMASHITA Shunichi', 18)}}的其他基金

Molecular epidemiological study of thyroid cancers by international collaboration
国际合作的甲状腺癌分子流行病学研究
  • 批准号:
    16H02774
  • 财政年份:
    2016
  • 资助金额:
    --
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
Morphological analysis of mitochondria during mitophagy
线粒体自噬过程中线粒体的形态学分析
  • 批准号:
    15K18501
  • 财政年份:
    2015
  • 资助金额:
    --
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
Elucidation of Prognostic Markers and their Molecular Mechanism for Thyroid Cancer
甲状腺癌预后标志物及其分子机制的阐明
  • 批准号:
    26293222
  • 财政年份:
    2014
  • 资助金额:
    --
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Provocative epidemiological study on identification of factor of thyroid carcinogenesis
甲状腺癌发生因素鉴定的前瞻性流行病学研究
  • 批准号:
    26670460
  • 财政年份:
    2014
  • 资助金额:
    --
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
Molecular Epidemiological Study on Risk of Radiation-associated Cancer after the Chernobyl Nuclear Power Plant accident
切尔诺贝利核电站事故后辐射相关癌症风险的分子流行病学研究
  • 批准号:
    25257508
  • 财政年份:
    2013
  • 资助金额:
    --
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
Large-scale cohort molecular epidemiological study after the Chernobyl accident
切尔诺贝利事故后大规模队列分子流行病学研究
  • 批准号:
    22256004
  • 财政年份:
    2010
  • 资助金额:
    --
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
Elucidation of molecular mechanism on thyroid carcinogenesis anddevelopmental application of molecular targeting therapy
甲状腺癌发生分子机制阐明及分子靶向治疗的发展应用
  • 批准号:
    22390189
  • 财政年份:
    2010
  • 资助金额:
    --
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Long-term molecular epidemiological studies on thyroid cancers around Chernobyl
切尔诺贝利周围甲状腺癌的长期分子流行病学研究
  • 批准号:
    19256003
  • 财政年份:
    2007
  • 资助金额:
    --
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
Elucidation of thyroid carcinogenesis and clinical application of molecular targeting therapy
甲状腺癌发生机制的阐明及分子靶向治疗的临床应用
  • 批准号:
    19390253
  • 财政年份:
    2007
  • 资助金额:
    --
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Molecular Epidemiology of Thyroid Diseases around Semiparatinsk, Kazakhstan and Altai region, Russia
哈萨克斯坦塞米帕拉金斯克和俄罗斯阿尔泰地区甲状腺疾病的分子流行病学
  • 批准号:
    12576020
  • 财政年份:
    2000
  • 资助金额:
    --
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)

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American Hibakusha: Radiation Affected Communities Inside of the United States of America
美国原爆幸存者:美利坚合众国境内受辐射影响的社区
  • 批准号:
    20H01228
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Hibakusha Lives and Collective Memory Communities in the 21st Century
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被污染的生命:核时代日本的原爆幸存者
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用英语理解和传达原爆幸存者证词的跟踪调查:信息解释和变化的分析
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