Development of Reaction and Analysis Systems based on Liquid / Liquid Interfaces

基于液/液界面的反应和分析系统的开发

基本信息

批准号：
13853004
负责人：
KITAMURA Noboru
金额：
$ 73.8万
依托单位：
Hokkaido University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (S)
财政年份：
2001
资助国家：
日本
起止时间：
2001 至 2005
项目状态：
已结题

项目摘要

Chemistry in Oil-in-Water Emulsion and Single Microdroplets/Water Systems : On the basis of the knowledge about ion/mass transfer across oil/water interfaces, new and novel photoreactions of single microdroplets in water have been developed. In the case of a photocyanation reaction of pyrene via a photoinduced electron transfer mechanism (PET), photoirradiation of benzonitrile microdroplets containing pyrene and 1,4-dicyanobenzene dispersed in an aqueous NaCN solution gave rise to formation of 1-cyanopyrene with the quantum yield of 0.68 under the optimum conditions. Analogous photoreactions were developed for carbazole derivatives and other aromatic hydrocarbons.Oil/Water Interfacial Systems in Microchannel Chips : Photchemical, electrochemical, and thermal reactions were explored in polymer microchannel, microchannel-microelectrode, or microchannel-microheter chips. As a typical example, the photocyanation reaction of pyrene via a PET mechanism mentioned above was conducted in microc … More hannel chips. An aqueous NaCN solution and a propylene carbonate solution of pyrene and 1,4-dicyanobenzene were introduced to a microchannel chip at the same flow velocity and the whole of the chip was irradiated. The photocyanation reaction of pyrene proceeded along parallel solution flow in the microchannel with the yield of 72% and the reaction time of 210 s. Furthermore, 1-cyanopyrene as a product was extracted completely into the oil phase. A photochemical microreactor was thus demonstrated.Laser-Induced Photo-Thermal Liquid-to-Droplet Extraction : A novel method of laser-induced microdroplet formation was developed and the phenomena was applied to liquid-to-single microdroplet extraction of a solute. When an aqueous triethylamine (TEA) solution was irradiated by a focused 1064 nm laser beam under an optical microscope, a single TEA microdroplet was produced by photo-thermal effects of the solution. The droplet was optically trapped simultaneously. In the presence of p-chlorophenol in aqueous TEA solution, laser irradiation gave rise to single microdroplet formation and simultaneous liquid-to-TEA droplet extraction of p-chlorophenol as revealed by in situ Raman microspectroscopy. The extraction efficiency in the single microdroplet system was shown to be much higher than that in the relevant bulk solution system. Analogous laser-induced liquid-to-droplet extraction was confirmed in an aqueous 1-BuOH solution. On the basis of fluorescence microspectroscopy, a solute as low as 10-8 M was simultaneously concentrated and detected by the laser-induced method. Less

水中油乳液和单微粒/水系统中的化学：基于关于跨油/水接口的离子/传质的知识，已经开发了水中的单个微螺旋体的新的和新颖的光反应。在通过光诱导的电子转移机制（PET）进行光跨反应的情况下，在水NACN溶液中含有pyr烯的苯硝基苯二烯微苯二酚和1,4-二苯乙烯的光辐照与1 cyanopyrene的质量产生，在水NACN溶液中抗衡，从而形成了0.68的量子。开发了针对甲Bazole衍生物和其他芳族碳氢化合物的类似的光反应。微通道芯片中的油/水界面系统：在聚合物微传输量，微型机械通道，微型渠道 - 纳尔米色电极，或微观电极芯片中，探索了光化学，电化学和热反应。作为一个典型的例子，在microc中进行了pyrene通过上述PET机制的光氨基化反应……更多的Hannel芯片。将pyrene水溶液和1,4-二甲苯的丙烯酸溶液和1,4-二苯乙烯溶液以相同的流速度引入微通道芯片，并辐照整个芯片。 pyrene的光氨基化反应沿微通道中的平行溶液流进行，产率为72％，反应时间为210 s。此外，将1-苯甲吡啶作为产物完全提取到石油相中。因此，证明了光化学微反应器。激光器诱导的光液液体对嗜血杆萃取：开发了激光诱导的微滴形成的新方法，并将现象应用于溶液的液态至单一微粒萃取。当在光学显微镜下聚焦的1064 nm激光束辐射三乙胺（TEA）溶液时，通过溶液的光热效应产生了单个茶微粒。液滴很容易被捕获。在水溶液中存在P-氯苯酚的情况下，激光照射会引起单个微孔形成，并在原位拉曼微光谱镜上揭示了P-氯苯酚的简单液体到淡淡的液滴提取。单个微副系统中的提取效率比相关的大量解决方案系统中的提取效率高得多。在1-BUOH水溶液中证实了无效激光引起的液体到滴头提取。基于荧光微光谱法，简单地浓缩了低至10-8 m的固体，并通过激光诱导的方法检测到。较少的