Development of the flexible scaffolds of aortic stent grafts, which can be applied to the curvature repeatedly. -Also for application to the biodegradable stent grafts-

主动脉支架植入术是高危主动脉瘤手术的最有前途的替代方案之一，但有时会导致悲剧。然而，我们需要克服一些问题才能适用于许多情况。由于支架移植物的支架是刚性金属弹簧模式，很难调整到不能重复输送的位置。在本研究中，我们试图开发一种可重复应用于弯曲的主动脉支架的柔性支架。这种新型支架是由软管气球制成的，当它们被液体加压时，可以形成设计的形状。脚手架在没有压力的情况下，可以折叠到小直径的输送鞘中，可以顺行输送。支架移植物还可以在液体压力开关的情况下重复输送。当管道球囊本身由可生物降解聚合物制成时，支架可应用于可生物降解支架移植物。支架移植模型成功地形成了初步研究中设计的模型。然而，最后，我们无法开发出足够坚固的脚手架来进行交付操作。我们的结论是，开发团队需要非常高的技术来制作管状气球

Aortic stent grafting is one of the most promising alternatives to the high-risked aortic arch aneurysm operations, which sometimes result in the tragedies. However, we need to overcome some problems to apply to many cases. Since the scaffolds of the stent grafts are mode of stiff metal springs, it is difficult to adjust them to the cannot be delivered repeatedly. In this study, we tried to develop the flexible scaffolds of aortic stent grafts, which can be applied to the curvature repeatedly. The new scaffolds are made of flexible tube balloons, which can be formed the designed shape when they are pressurized by liquid. Without pressure, he scaffolds can be folded into the delivery sheaths with the small diameters, which can be delivered antegradely. The stent grafts also can be delivered repeatedly, with the liquid pressure on and off. The scaffold can be applied to the biodegradable stent grafts when the tube balloon itself is made of biodegradable polymers. The stent graft models were successful to be shaped as designed in the preliminary study. However finally, we were not able to develop the scaffolds strong enough for delivery operation. We concluded that developing team needed very high technology to from the tube balloons