Improvement of wear resistance and safety of cobalt-chromium alloys for metal-on-metal type artificial joint

金属对金属型人工关节用钴铬合金耐磨性和安全性的提高

• 批准号: 14350375
• 负责人: HANAWA Takao
• 金额: $ 9.47万
• 依托单位: Tokyo Medical and Dental University (2004-2005)National Institute for Materials Science (2002-2003)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14350375/
• 关键词: Cobalt-chromium ally; Wear resistance; Ion implantation; Friction coefficient; Surface analysis; Corrosion resistance; Artificial joint; ニッケルフリー合金; 摩擦摩耗試験; 金属イオン溶出; 表面組成; 窒素イオン注入

Friction-wear properties of a Co-29mass%Cr-6mass%Mo alloy (ASTM F799-95) but reducing the amount of nickel were evaluated with friction-wear test using a pin-on-flat type reciprocating friction tester in air and phosphate buffered saline, PBS(-), as a quasi-biological environment under applied stress of 1.0, 3.5 and 5.0MPa to understand the performance of this alloy for metal-on-metal type artificial hip joints. In addition, metal ions dissolved in PBS(-) after the test was quantified. As a result, wear loss in PBS(-) is much smaller than that in air and increases with the increase of applied stress in both air and PBS(-), while the coefficient of friction in steady state during the test is larger in PBS(-) than in air. Wear damage in PBS(-) is smaller than that in air, however more small scale of irregularity is observed in PBS(-) than that in air.Nitrogen ions were implanted in the alloy with reducing the amount of nickel in order to improve the friction-wear properties. The friction … More -wear properties of unimplanted and nitrogen-ion-implanted Co-Cr-Mo alloys were evaluated. As a result, the wear loss in PBS(-) was much smaller than that in air and increased with the increase of applied stress in both air and PBS(-), while the friction coefficient in a steady state during the test was larger in PBS(-) than in air, according to the lubrication behaviors of wear debris and PBS(-). Nitrogen-ion implantation is effective to decrease the friction coefficient in PBS(-) at the sliding interface between mutual Co-Cr-Mo alloys as well as to decrease the wear debris in PBS(-).Changes in the composition of the surface layer of the alloy with ion implantation, autoclaving, and immersion in Hanks' solution as a simulated body fluid were characterized using X-ray photoelectron spectroscopy to evaluate the stability of the material and predict the safety and tissue compatibility of the material. After N-implantation, nitrogen atoms existed as cobalt nitride in the substrate just under the surface oxide and NH_3 or NH_4 in the surface oxide, and these amounts increased with the increase of the dose. Chromium was concentrated in the surface oxide but depleted in the substrate with ion implantation. Cobalt was preferentially oxidized by autoclaving and depleted in the substrate after autoclaving. Less

采用销平式往复摩擦磨损试验机，在空气和磷酸盐缓冲盐水PbS(-)的准生物环境中，分别在1.0、3.5和5.0 MPa的应力作用下，评价了Co-29mas%Cr6mas%Mo合金(ASTM F799-95)在减少镍含量的情况下的摩擦磨损性能，以了解该合金在金属对金属类型人工髋关节中的性能。此外，还对试验后溶解在PbS(-)中的金属离子进行了定量。结果表明，PbS(-)的磨损量远小于空气中的磨损量，且随着空气和PbS(-)中外加应力的增加而增加，而PbS(-)中的稳态摩擦系数大于空气中的磨损量。PbS(-)中的磨损损伤比空气中的小，而PbS(-)中的不规则性比空气中的小。为了改善摩擦磨损性能，在合金中注入氮离子以减少镍的含量。The Friction…对未注入和氮离子注入的Co-Cr-Mo合金的耐磨性能进行了评价。结果表明，PbS(-)的磨损量远小于空气中的磨损量，且随着空气和PbS(-)中外加应力的增加而增加，而根据磨屑和PbS(-)的润滑行为，PbS(-)中的稳态摩擦系数大于空气中的摩擦系数。氮离子注入有效地降低了PbS(-)中Co-Cr-Mo合金滑动界面的摩擦系数，减少了PbS(-)中的磨屑。用X射线光电子能谱表征了离子注入、高压灭菌和模拟体液浸泡后PbS(-)合金表层成分的变化，以评价材料的稳定性，预测材料的安全性和组织相容性。氮离子注入后，氮原子以氮化钴的形式存在于衬底表面氧化物的正下方，而氮原子则以NH_3或NH_4的形式存在于表面氧化物中，且随着注入剂量的增加而增加。离子注入后，铬在表面氧化物中集中，而在衬底中贫化。在高压灭菌过程中，钴优先被氧化，在高压灭菌后，钴在衬底中被耗尽。较少

项目成果

Friction-wear properties of nitrogen-ion-implanted nickel-free Co-Cr-Mo alloy

氮离子注入无镍Co-Cr-Mo合金的摩擦磨损性能

• 发表时间: 2005
• 期刊: Materials Transactions 46・7
• 作者: T.Hanawa;K.Nakazawa;K.Kano;S.Hiromoto;Y.Suzuki;A.Yamamoto
• 通讯作者: A.Yamamoto

物質・材料工学と社会

材料/材料工程与社会

• 发表时间: 2005
• 作者: Yasuo Tomita;Yoshitsugu Hayashi;Kenji Doi;T.Seki;大津 政康共著
• 通讯作者: 大津 政康共著

Metal ion release from metal implants

• DOI: 10.1016/j.msec.2004.08.018
• 发表时间: 2004-12-01
• 期刊: MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS
• 作者: Hanawa, T

塙 隆夫: "Reconstitution and regeneration of surface oxide film on metallic materials in biological environments"Corrosion Reviews. 21(2-3). 161-181 (2003)

Takao Hanawa：“生物环境中金属材料表面氧化膜的重建和再生”腐蚀评论21（2-3）（2003）。

Engineering Materials for Biomedical Applications, Chapter 4, Surface modification of metallic biomaterials

生物医学应用工程材料，第 4 章，金属生物材料的表面改性

• 发表时间: 2004
• 作者: 岸 輝雄;小口信行;塙 隆夫;T.Hanawa
• 通讯作者: T.Hanawa