Establishment of support technology for the development of surgical training simulator

手术训练模拟器开发支撑技术的建立

• 批准号: 14370419
• 负责人: UMEZU Mitsuo
• 金额: $ 8.77万
• 依托单位: Waseda University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14370419/
• 关键词: Artificial organ technology; Living system; Cardiovascular disease; Mock circulatory system; 僧帽弁閉鎖不全; 人工弁輪; 循環シミュレータ; 弁形成術; ブタ僧帽弁; 僧帽弁逆流量; 有効弁口面積; 患者ロボット; 僧帽弁形成術; 手術訓練用シミュレータ; 荷重; Rigid ring; Flexible ring

In order to discuss a selection criteria for surgical technique on cardiovascular diseases, it is effective to make use of a mock circulatory system. In this study, mitral regurgitation is focused for the development of surgical training simulator. At first reproduction of mitral regurgitation was achieved. Then quantitative evaluation of the mitral valvuloplasty were performed as an application of the in vitro simulator.1.Reproduction of mitral regurgitationA fresh porcine mitral valve with chordae and papillary muscles was installed into the mitral position of the mock circuit. The evaluation system is capable of simulating various mitral conditions by changing the valve orientation. The normal model was implemented with the papillary muscle in the same configuration as in a natural heart. In contrast, the prolapse model was produced by severing anterior marginal chordae. As a result, valve closure similar to a natural heart was successfully attained in the normal model.2.Evaluation of the effectiveness of mitral valvuloplastyA comparative test was conducted to evaluate the effectiveness of mitral valvuloplasty techniques for the repair of an anterior mitral leaflet prolapse. In order to correct the prolapsed portion of mitral valve, the chordal replacement (replacement model) and the edge-to-edge technique (Edge-to-Edge model) were applied by an experienced surgeon. After the application of the two, the prolapsed portion was corrected in systole, and a double orifice area of E-to-E model was observed in diastole.In conclusion, it has been confirmed that the mock system developed in this study can provide useful data for cardiac surgeons. As the data can be treated quantitatively, surgeons and biomedical engineers can discuss on the scientific basis.

为了探讨心血管疾病手术技术的选择标准，利用模拟循环系统是有效的。在本研究中，二尖瓣反流的重点是外科训练模拟器的开发。首先实现了二尖瓣反流的再现。应用体外模拟器对二尖瓣成形术进行定量评价。二尖瓣反流的复制将一个新鲜的猪二尖瓣与索状肌和乳头肌安装在模拟回路的二尖瓣位置。该评估系统能够通过改变二尖瓣朝向来模拟各种二尖瓣状态。正常模型的乳头肌结构与天然心脏相同。相反，脱垂模型是通过切断前边缘脊索产生的。结果，在正常模型中成功地获得了与天然心脏相似的瓣膜关闭。评价二尖瓣成形术的有效性进行了一项比较试验，以评估二尖瓣成形术修复前二尖瓣小叶脱垂的有效性。为了矫正二尖瓣脱垂部分，由经验丰富的外科医生采用索索置换术（置换模型）和边缘到边缘技术（边缘到边缘模型）。两者应用后，收缩期矫正脱垂部分，舒张期观察E-to-E模型双孔面积。总之，本研究开发的模拟系统可以为心脏外科医生提供有用的数据。由于数据可以定量处理，外科医生和生物医学工程师可以在科学的基础上进行讨论。

项目成果

梅津光生, 岩崎清隆, 桜井靖久, 岡野光夫: "生命理工学専攻にみる医工連携の実践的教育,研究"日本機械学会第16回バイオエンジニアリング講演会講演論文集. 337-338 (2004)

Mitsuo Umezu、Kiyotaka Iwasaki、Yasuhisa Sakurai、Mitsuo Okano：“生命科学与工程系医学工程合作的实践教育和研究”第 16 届日本机械工程学会生物工程会议论文集 337-338（2004 年）。 ）

梅津光生, 他: "人工心臓の耐久性を予測する上での留意点"第31回人工心臓と補助循環懇話会. 21 (2003)

Mitsuo Umezu 等人：“预测人造心脏耐久性时要记住的要点”第 31 届人造心脏和辅助循环会议 21 (2003)。

血液循環モデルの人工臓器評価への応用

血液循环模型在人工器官评价中的应用

• 发表时间: 2004
• 期刊: 生体医工学 42
• 作者: 梅津光生;岩崎清隆;白石泰之他
• 通讯作者: 白石泰之他

僧帽弁手術をサポートする血液循環シミュレータの開発

开发支持二尖瓣手术的血液循环模拟器

• 发表时间: 2004
• 期刊: 人工臓器 33
• 作者: 梅津光生;土井博文;野田怜子他
• 通讯作者: 野田怜子他

Biomedical engineering analysis on the effectiveness of cardiovascular surgery : Anastomosis methods for coronary artery bypass grafting

心血管手术有效性的生物医学工程分析：冠状动脉搭桥术的吻合方法

• 发表时间: 2004
• 期刊: 7^<th> Polish-Japanese seminar on new technologies for future artificial ograns 7
• 作者: M.Umezu;J.Kawai;J.Suehiro;et al.
• 通讯作者: et al.